Back to Multiple platform build/check report for BioC 3.21:   simplified   long
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This page was generated on 2025-03-21 11:47 -0400 (Fri, 21 Mar 2025).

HostnameOSArch (*)R versionInstalled pkgs
nebbiolo1Linux (Ubuntu 24.04.1 LTS)x86_64R Under development (unstable) (2025-03-13 r87965) -- "Unsuffered Consequences" 4777
palomino7Windows Server 2022 Datacenterx64R Under development (unstable) (2025-03-01 r87860 ucrt) -- "Unsuffered Consequences" 4545
lconwaymacOS 12.7.1 Montereyx86_64R Under development (unstable) (2025-03-02 r87868) -- "Unsuffered Consequences" 4576
kjohnson3macOS 13.7.1 Venturaarm64R Under development (unstable) (2025-03-02 r87868) -- "Unsuffered Consequences" 4528
kunpeng2Linux (openEuler 24.03 LTS)aarch64R Under development (unstable) (2025-02-19 r87757) -- "Unsuffered Consequences" 4458
Click on any hostname to see more info about the system (e.g. compilers)      (*) as reported by 'uname -p', except on Windows and Mac OS X

Package 526/2313HostnameOS / ArchINSTALLBUILDCHECKBUILD BIN
decoupleR 2.13.0  (landing page)
Pau Badia-i-Mompel
Snapshot Date: 2025-03-20 13:40 -0400 (Thu, 20 Mar 2025)
git_url: https://git.bioconductor.org/packages/decoupleR
git_branch: devel
git_last_commit: 1d86763
git_last_commit_date: 2024-10-29 11:00:29 -0400 (Tue, 29 Oct 2024)
nebbiolo1Linux (Ubuntu 24.04.1 LTS) / x86_64  OK    OK    WARNINGS  UNNEEDED, same version is already published
palomino7Windows Server 2022 Datacenter / x64  OK    OK    WARNINGS    OK  UNNEEDED, same version is already published
lconwaymacOS 12.7.1 Monterey / x86_64  OK    OK    WARNINGS    OK  UNNEEDED, same version is already published
kjohnson3macOS 13.7.1 Ventura / arm64  OK    OK    ERROR    OK  
kunpeng2Linux (openEuler 24.03 LTS) / aarch64  OK    OK    ERROR  


CHECK results for decoupleR on kunpeng2

To the developers/maintainers of the decoupleR package:
- Allow up to 24 hours (and sometimes 48 hours) for your latest push to git@git.bioconductor.org:packages/decoupleR.git to reflect on this report. See Troubleshooting Build Report for more information.
- Use the following Renviron settings to reproduce errors and warnings.
- If 'R CMD check' started to fail recently on the Linux builder(s) over a missing dependency, add the missing dependency to 'Suggests:' in your DESCRIPTION file. See Renviron.bioc for more information.
- See Martin Grigorov's blog post for how to debug Linux ARM64 related issues on a x86_64 host.

raw results


Summary

Package: decoupleR
Version: 2.13.0
Command: /home/biocbuild/R/R/bin/R CMD check --install=check:decoupleR.install-out.txt --library=/home/biocbuild/R/R/site-library --no-vignettes --timings decoupleR_2.13.0.tar.gz
StartedAt: 2025-03-21 05:49:39 -0000 (Fri, 21 Mar 2025)
EndedAt: 2025-03-21 05:59:50 -0000 (Fri, 21 Mar 2025)
EllapsedTime: 611.4 seconds
RetCode: 1
Status:   ERROR  
CheckDir: decoupleR.Rcheck
Warnings: NA

Command output

##############################################################################
##############################################################################
###
### Running command:
###
###   /home/biocbuild/R/R/bin/R CMD check --install=check:decoupleR.install-out.txt --library=/home/biocbuild/R/R/site-library --no-vignettes --timings decoupleR_2.13.0.tar.gz
###
##############################################################################
##############################################################################


* using log directory ‘/home/biocbuild/bbs-3.21-bioc/meat/decoupleR.Rcheck’
* using R Under development (unstable) (2025-02-19 r87757)
* using platform: aarch64-unknown-linux-gnu
* R was compiled by
    aarch64-unknown-linux-gnu-gcc (GCC) 14.2.0
    GNU Fortran (GCC) 14.2.0
* running under: openEuler 24.03 (LTS-SP1)
* using session charset: UTF-8
* using option ‘--no-vignettes’
* checking for file ‘decoupleR/DESCRIPTION’ ... OK
* checking extension type ... Package
* this is package ‘decoupleR’ version ‘2.13.0’
* package encoding: UTF-8
* checking package namespace information ... OK
* checking package dependencies ... OK
* checking if this is a source package ... OK
* checking if there is a namespace ... OK
* checking for hidden files and directories ... OK
* checking for portable file names ... OK
* checking for sufficient/correct file permissions ... OK
* checking whether package ‘decoupleR’ can be installed ... OK
* checking installed package size ... OK
* checking package directory ... OK
* checking ‘build’ directory ... OK
* checking DESCRIPTION meta-information ... OK
* checking top-level files ... OK
* checking for left-over files ... OK
* checking index information ... OK
* checking package subdirectories ... OK
* checking code files for non-ASCII characters ... OK
* checking R files for syntax errors ... OK
* checking whether the package can be loaded ... OK
* checking whether the package can be loaded with stated dependencies ... OK
* checking whether the package can be unloaded cleanly ... OK
* checking whether the namespace can be loaded with stated dependencies ... OK
* checking whether the namespace can be unloaded cleanly ... OK
* checking loading without being on the library search path ... OK
* checking dependencies in R code ... NOTE
[2025-03-21 05:50:21] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-21 05:50:21] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-21 05:50:21] [INFO]    [OmnipathR] Initialized cache: `/home/biocbuild/.cache/OmnipathR`.
[2025-03-21 05:50:21] [INFO]    [OmnipathR] Package `OmnipathR` packaged: NA
[2025-03-21 05:50:21] [INFO]    [OmnipathR] Package `OmnipathR` date/publication: 2025-03-20
[2025-03-21 05:50:21] [INFO]    [OmnipathR] Package `OmnipathR` built: R 4.5.0; ; 2025-03-20 19:21:27 UTC; unix
[2025-03-21 05:50:21] [INFO]    [OmnipathR] Package `OmnipathR` version: 3.15.11
[2025-03-21 05:50:21] [INFO]    [OmnipathR] Package `OmnipathR` repository: Bioconductor 3.21
[2025-03-21 05:50:21] [INFO]    [OmnipathR] Session info: [version=R Under development (unstable) (2025-02-19 r87757); os=openEuler 24.03 (LTS-SP1); system=aarch64, linux-gnu; ui=X11; language=(EN); collate=C; ctype=en_US.UTF-8; tz=UTC; date=2025-03-21; pandoc=2.12 @ /home/biocbuild/bin/ (via rmarkdown); quarto=NA]
[2025-03-21 05:50:21] [INFO]    [OmnipathR] External libraries: [cairo=1.18.0; cairoFT=; pango=1.51.0; png=1.6.40; jpeg=6.2; tiff=LIBTIFF, Version 4.6.0; tcl=8.6.14; curl=8.4.0; zlib=1.2.13; bzlib=1.0.8, 13-Jul-2019; xz=5.4.7; deflate=; PCRE=10.42 2022-12-11; ICU=74.1; TRE=TRE 0.8.0 R_fixes (BSD); iconv=glibc 2.38; readline=8.2; BLAS=/home/biocbuild/R/R-devel_2025-02-19/lib/libRblas.so; lapack=/home/biocbuild/R/R-devel_2025-02-19/lib/libRlapack.so; lapack_version=3.12.0]
[2025-03-21 05:50:21] [INFO]    [OmnipathR] Loaded packages: abind 1.4-8(2024-09-12); annotate 1.85.0(2025-03-20); AnnotationDbi 1.69.0(2025-03-20); AUCell 1.29.0(2025-03-20); backports 1.5.0(2024-05-23); beachmat 2.23.7(2025-03-20); Biobase 2.67.0(2025-03-20); BiocGenerics 0.53.6(2025-03-20); BiocParallel 1.41.2(2025-03-20); BiocSingular 1.23.0(2025-03-20); Biostrings 2.75.4(2025-03-20); bit 4.6.0(2025-03-06); bit64 4.6.0-1(2025-01-16); blob 1.2.4(2023-03-17); cachem 1.1.0(2024-05-16); cellranger 1.1.0(2016-07-27); checkmate 2.3.2(2024-07-29); chromote 0.4.0(2025-01-25); cli 3.6.4(2025-02-13); codetools 0.2-20(2024-03-31); crayon 1.5.3(2024-06-20); curl 6.2.1(2025-02-19); data.table 1.17.0(2025-02-22); DBI 1.2.3(2024-06-02); decoupleR 2.13.0(2025-03-20); DelayedArray 0.33.6(2025-03-20); DelayedMatrixStats 1.29.1(2025-03-20); digest 0.6.37(2024-08-19); dplyr 1.1.4(2023-11-17); evaluate 1.0.3(2025-01-10); fastmap 1.2.0(2024-05-15); fs 1.6.5(2024-10-30); generics 0.1.3(2022-07-05); GenomeInfoDb 1.43.4(2025-03-20); GenomeInfoDbData 1.2.14(2025-03-12); GenomicRanges 1.59.1(2025-03-20); glue 1.8.0(2024-09-30); graph 1.85.3(2025-03-20); GSEABase 1.69.1(2025-03-20); GSVA 2.1.9(2025-03-20); h5mread 0.99.4(2025-03-20); HDF5Array 1.35.16(2025-03-20); hms 1.1.3(2023-03-21); htmltools 0.5.8.1(2024-04-04); httr 1.4.7(2023-08-15); httr2 1.1.1(2025-03-08); igraph 2.1.4(2025-01-23); IRanges 2.41.3(2025-03-20); irlba 2.3.5.1(2022-10-03); jsonlite 1.9.1(2025-03-03); KEGGREST 1.47.0(2025-03-20); knitr 1.50(2025-03-16); later 1.4.1(2024-11-27); lattice 0.22-6(2024-03-20); lifecycle 1.0.4(2023-11-07); logger 0.4.0(2024-10-22); lubridate 1.9.4(2024-12-08); magick 2.8.5(2024-09-20); magrittr 2.0.3(2022-03-30); Matrix 1.7-3(2025-03-11); MatrixGenerics 1.19.1(2025-03-20); matrixStats 1.5.0(2025-01-07); memoise 2.0.1(2021-11-26); OmnipathR 3.15.11(2025-03-20); parallelly 1.42.0(2025-01-30); pillar 1.10.1(2025-01-07); pkgconfig 2.0.3(2019-09-22); png 0.1-8(2022-11-29); prettyunits 1.2.0(2023-09-24); processx 3.8.6(2025-02-21); progress 1.2.3(2023-12-06); promises 1.3.2(2024-11-28); ps 1.9.0(2025-02-18); purrr 1.0.4(2025-02-05); R.methodsS3 1.8.2(2022-06-13); R.oo 1.27.0(2024-11-01); R.utils 2.13.0(2025-02-24); R6 2.6.1(2025-02-15); rappdirs 0.3.3(2021-01-31); Rcpp 1.0.14(2025-01-12); readr 2.1.5(2024-01-10); readxl 1.4.5(2025-03-07); rhdf5 2.51.2(2025-03-20); rhdf5filters 1.19.2(2025-03-20); Rhdf5lib 1.29.1(2025-03-20); rjson 0.2.23(2024-09-16); rlang 1.1.5(2025-01-17); rmarkdown 2.29(2024-11-04); RSQLite 2.3.9(2024-12-03); rsvd 1.0.5(2021-04-16); rvest 1.0.4(2024-02-12); S4Arrays 1.7.3(2025-03-20); S4Vectors 0.45.4(2025-03-20); ScaledMatrix 1.15.0(2025-03-20); sessioninfo 1.2.3(2025-02-05); SingleCellExperiment 1.29.2(2025-03-20); SparseArray 1.7.7(2025-03-20); sparseMatrixStats 1.19.0(2025-03-20); SpatialExperiment 1.17.0(2025-03-20); stringi 1.8.4(2024-05-06); stringr 1.5.1(2023-11-14); SummarizedExperiment 1.37.0(2025-03-20); tibble 3.2.1(2023-03-20); tidyr 1.3.1(2024-01-24); tidyselect 1.2.1(2024-03-11); timechange 0.3.0(2024-01-18); tzdb 0.5.0(2025-03-15); UCSC.utils 1.3.1(2025-03-20); vctrs 0.6.5(2023-12-01); websocket 1.4.2(2024-07-22); withr 3.0.2(2024-10-28); xfun 0.51(2025-02-19); XML 3.99-0.18(2025-01-01); xml2 1.3.8(2025-03-14); xtable 1.8-4(2019-04-21); XVector 0.47.2(2025-03-20); yaml 2.3.10(2024-07-26); zip 2.3.2(2025-02-01)
[2025-03-21 05:50:21] [INFO]    [OmnipathR] CURL: version: 8.4.0; headers: 8.4.0; ssl_version: OpenSSL/3.0.12; libz_version: 1.2.13; libssh_version: libssh/0.10.5/openssl/zlib; libidn_version: 2.3.4; host: aarch64-openEuler-linux-gnu; protocols: dict, file, ftp, ftps, gopher, gophers, http, https, imap, imaps, ldap, ldaps, mqtt, pop3, pop3s, rtsp, scp, sftp, smb, smbs, smtp, smtps, telnet, tftp; ipv6: TRUE; http2: TRUE; idn: TRUE; url_parser: TRUE
[2025-03-21 05:50:21] [TRACE]   [OmnipathR] Running on a build server, wiping cache.
[2025-03-21 05:50:21] [TRACE]   [OmnipathR] Cache is at `/home/biocbuild/.cache/OmnipathR`.
[2025-03-21 05:50:21] [TRACE]   [OmnipathR] Contains 4 files.
[2025-03-21 05:50:21] [TRACE]   [OmnipathR] Cache is locked: FALSE.
[2025-03-21 05:50:21] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-21 05:50:21] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-21 05:50:21] [SUCCESS] [OmnipathR] Removing all cache contents from `/home/biocbuild/.cache/OmnipathR`.
[2025-03-21 05:50:21] [TRACE]   [OmnipathR] Pandoc version: `2.12`.
[2025-03-21 05:50:21] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/R/R-devel_2025-02-19/site-library/OmnipathR/db/db_def.json` (encoding: UTF-8).
[2025-03-21 05:50:21] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-21 05:50:21] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/R/R-devel_2025-02-19/site-library/OmnipathR/internal/magic_bytes.json` (encoding: UTF-8).
[2025-03-21 05:50:21] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-21 05:50:21] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/R/R-devel_2025-02-19/site-library/OmnipathR/internal/urls.json` (encoding: UTF-8).
[2025-03-21 05:50:21] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-21 05:50:21] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/R/R-devel_2025-02-19/site-library/OmnipathR/internal/id_types.json` (encoding: UTF-8).
[2025-03-21 05:50:21] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-21 05:50:21] [TRACE]   [OmnipathR] Cache locked: FALSE
* checking S3 generic/method consistency ... OK
* checking replacement functions ... OK
* checking foreign function calls ... OK
* checking R code for possible problems ... OK
* checking Rd files ... OK
* checking Rd metadata ... OK
* checking Rd cross-references ... WARNING
Missing link(s) in Rd file 'run_gsva.Rd':
  ‘GSVA::gsva’ ‘GeneSetCollection’

Non-topic package-anchored link(s) in Rd file 'pipe.Rd':
  ‘[magrittr:pipe]{%>%}’

See section 'Cross-references' in the 'Writing R Extensions' manual.

Found the following Rd file(s) with Rd \link{} targets missing package
anchors:
  run_gsva.Rd: GSVA::gsva, GeneSetCollection
Please provide package anchors for all Rd \link{} targets not in the
package itself and the base packages.
* checking for missing documentation entries ... OK
* checking for code/documentation mismatches ... OK
* checking Rd \usage sections ... OK
* checking Rd contents ... OK
* checking for unstated dependencies in examples ... OK
* checking files in ‘vignettes’ ... OK
* checking examples ... OK
Examples with CPU (user + system) or elapsed time > 5s
                user system elapsed
get_dorothea  31.712  2.390  35.866
run_fgsea     25.991  0.789  26.914
run_aucell    11.160  2.096  13.623
get_collectri 10.358  0.835  19.396
get_progeny    7.141  0.491  16.706
* checking for unstated dependencies in ‘tests’ ... OK
* checking tests ...
  Running ‘testthat.R’
 ERROR
Running the tests in ‘tests/testthat.R’ failed.
Last 13 lines of output:
  [120] 0.112          | 0.112            [120]
  [121] 0.991          - 1.000            [121]
  [122] 0.991          - 1.000            [122]
  [123] 0.123          - 0.126            [123]
  [124] 0.123          - 0.126            [124]
  [125] 0.156          | 0.156            [125]
  [126] 0.156          | 0.156            [126]
  [127] 0.592          | 0.592            [127]
  
    `actual$p_value[132:139]`: 0.125 0.592 0.592 0.175 0.175 0.198 0.198 0.592
  `expected$p_value[132:139]`: 0.125 0.592 0.592 0.184 0.184 0.198 0.198 0.592
  
  [ FAIL 1 | WARN 9 | SKIP 0 | PASS 34 ]
  Error: Test failures
  Execution halted
* checking for unstated dependencies in vignettes ... OK
* checking package vignettes ... OK
* checking running R code from vignettes ... SKIPPED
* checking re-building of vignette outputs ... SKIPPED
* checking PDF version of manual ... OK
* DONE

Status: 1 ERROR, 1 WARNING, 1 NOTE
See
  ‘/home/biocbuild/bbs-3.21-bioc/meat/decoupleR.Rcheck/00check.log’
for details.


Installation output

decoupleR.Rcheck/00install.out

##############################################################################
##############################################################################
###
### Running command:
###
###   /home/biocbuild/R/R/bin/R CMD INSTALL decoupleR
###
##############################################################################
##############################################################################


* installing to library ‘/home/biocbuild/R/R-devel_2025-02-19/site-library’
* installing *source* package ‘decoupleR’ ...
** this is package ‘decoupleR’ version ‘2.13.0’
** using staged installation
** R
** inst
** byte-compile and prepare package for lazy loading
** help
*** installing help indices
*** copying figures
** building package indices
** installing vignettes
** testing if installed package can be loaded from temporary location
** testing if installed package can be loaded from final location
** testing if installed package keeps a record of temporary installation path
* DONE (decoupleR)

Tests output

decoupleR.Rcheck/tests/testthat.Rout.fail


R Under development (unstable) (2025-02-19 r87757) -- "Unsuffered Consequences"
Copyright (C) 2025 The R Foundation for Statistical Computing
Platform: aarch64-unknown-linux-gnu

R is free software and comes with ABSOLUTELY NO WARRANTY.
You are welcome to redistribute it under certain conditions.
Type 'license()' or 'licence()' for distribution details.

R is a collaborative project with many contributors.
Type 'contributors()' for more information and
'citation()' on how to cite R or R packages in publications.

Type 'demo()' for some demos, 'help()' for on-line help, or
'help.start()' for an HTML browser interface to help.
Type 'q()' to quit R.

> library(testthat)
> library(decoupleR)
> 
> test_check("decoupleR")

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[2025-03-21 05:54:19] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-21 05:54:19] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-21 05:54:19] [INFO]    [OmnipathR] Initialized cache: `/home/biocbuild/.cache/OmnipathR`.
[2025-03-21 05:54:19] [INFO]    [OmnipathR] Package `OmnipathR` packaged: NA
[2025-03-21 05:54:19] [INFO]    [OmnipathR] Package `OmnipathR` date/publication: 2025-03-20
[2025-03-21 05:54:19] [INFO]    [OmnipathR] Package `OmnipathR` built: R 4.5.0; ; 2025-03-20 19:21:27 UTC; unix
[2025-03-21 05:54:19] [INFO]    [OmnipathR] Package `OmnipathR` version: 3.15.11
[2025-03-21 05:54:19] [INFO]    [OmnipathR] Package `OmnipathR` repository: Bioconductor 3.21
[2025-03-21 05:54:19] [INFO]    [OmnipathR] Session info: [version=R Under development (unstable) (2025-02-19 r87757); os=openEuler 24.03 (LTS-SP1); system=aarch64, linux-gnu; ui=X11; language=C; collate=C; ctype=en_US.UTF-8; tz=UTC; date=2025-03-21; pandoc=2.12 @ /home/biocbuild/bin/ (via rmarkdown); quarto=NA]
[2025-03-21 05:54:19] [INFO]    [OmnipathR] External libraries: [cairo=1.18.0; cairoFT=; pango=1.51.0; png=1.6.40; jpeg=6.2; tiff=LIBTIFF, Version 4.6.0; tcl=8.6.14; curl=8.4.0; zlib=1.2.13; bzlib=1.0.8, 13-Jul-2019; xz=5.4.7; deflate=; PCRE=10.42 2022-12-11; ICU=74.1; TRE=TRE 0.8.0 R_fixes (BSD); iconv=glibc 2.38; readline=8.2; BLAS=/home/biocbuild/R/R-devel_2025-02-19/lib/libRblas.so; lapack=/home/biocbuild/R/R-devel_2025-02-19/lib/libRlapack.so; lapack_version=3.12.0]
[2025-03-21 05:54:19] [INFO]    [OmnipathR] Loaded packages: abind 1.4-8(2024-09-12); annotate 1.85.0(2025-03-20); AnnotationDbi 1.69.0(2025-03-20); AUCell 1.29.0(2025-03-20); backports 1.5.0(2024-05-23); beachmat 2.23.7(2025-03-20); Biobase 2.67.0(2025-03-20); BiocGenerics 0.53.6(2025-03-20); BiocParallel 1.41.2(2025-03-20); BiocSingular 1.23.0(2025-03-20); Biostrings 2.75.4(2025-03-20); bit 4.6.0(2025-03-06); bit64 4.6.0-1(2025-01-16); blob 1.2.4(2023-03-17); brio 1.1.5(2024-04-24); broom 1.0.7(2024-09-26); cachem 1.1.0(2024-05-16); cellranger 1.1.0(2016-07-27); checkmate 2.3.2(2024-07-29); class 7.3-23(2025-01-01); cli 3.6.4(2025-02-13); codetools 0.2-20(2024-03-31); colorspace 2.1-1(2024-07-26); cowplot 1.1.3(2024-01-22); crayon 1.5.3(2024-06-20); curl 6.2.1(2025-02-19); data.table 1.17.0(2025-02-22); DBI 1.2.3(2024-06-02); decoupleR 2.13.0(2025-03-20); DelayedArray 0.33.6(2025-03-20); DelayedMatrixStats 1.29.1(2025-03-20); desc 1.4.3(2023-12-10); digest 0.6.37(2024-08-19); dplyr 1.1.4(2023-11-17); e1071 1.7-16(2024-09-16); evaluate 1.0.3(2025-01-10); fastmap 1.2.0(2024-05-15); fastmatch 1.1-6(2024-12-23); fgsea 1.33.4(2025-03-20); fs 1.6.5(2024-10-30); generics 0.1.3(2022-07-05); GenomeInfoDb 1.43.4(2025-03-20); GenomeInfoDbData 1.2.14(2025-03-12); GenomicRanges 1.59.1(2025-03-20); ggplot2 3.5.1(2024-04-23); glue 1.8.0(2024-09-30); graph 1.85.3(2025-03-20); GSEABase 1.69.1(2025-03-20); GSVA 2.1.9(2025-03-20); gtable 0.3.6(2024-10-25); h5mread 0.99.4(2025-03-20); HDF5Array 1.35.16(2025-03-20); hms 1.1.3(2023-03-21); htmltools 0.5.8.1(2024-04-04); htmlwidgets 1.6.4(2023-12-06); httr 1.4.7(2023-08-15); httr2 1.1.1(2025-03-08); igraph 2.1.4(2025-01-23); IRanges 2.41.3(2025-03-20); irlba 2.3.5.1(2022-10-03); jsonlite 1.9.1(2025-03-03); KEGGREST 1.47.0(2025-03-20); kernlab 0.9-33(2024-08-13); KernSmooth 2.23-26(2025-01-01); knitr 1.50(2025-03-16); later 1.4.1(2024-11-27); lattice 0.22-6(2024-03-20); lazyeval 0.2.2(2019-03-15); lifecycle 1.0.4(2023-11-07); logger 0.4.0(2024-10-22); lubridate 1.9.4(2024-12-08); magick 2.8.5(2024-09-20); magrittr 2.0.3(2022-03-30); MASS 7.3-65(2025-02-28); Matrix 1.7-3(2025-03-11); MatrixGenerics 1.19.1(2025-03-20); matrixStats 1.5.0(2025-01-07); memoise 2.0.1(2021-11-26); mixtools 2.0.0.1(2025-03-08); munsell 0.5.1(2024-04-01); nlme 3.1-167(2025-01-27); OmnipathR 3.15.11(2025-03-20); parallelly 1.42.0(2025-01-30); pillar 1.10.1(2025-01-07); pkgconfig 2.0.3(2019-09-22); plotly 4.10.4(2024-01-13); png 0.1-8(2022-11-29); prettyunits 1.2.0(2023-09-24); progress 1.2.3(2023-12-06); proxy 0.4-27(2022-06-09); purrr 1.0.4(2025-02-05); R.methodsS3 1.8.2(2022-06-13); R.oo 1.27.0(2024-11-01); R.utils 2.13.0(2025-02-24); R6 2.6.1(2025-02-15); ranger 0.17.0(2024-11-08); rappdirs 0.3.3(2021-01-31); Rcpp 1.0.14(2025-01-12); readr 2.1.5(2024-01-10); readxl 1.4.5(2025-03-07); rhdf5 2.51.2(2025-03-20); rhdf5filters 1.19.2(2025-03-20); Rhdf5lib 1.29.1(2025-03-20); rjson 0.2.23(2024-09-16); rlang 1.1.5(2025-01-17); rmarkdown 2.29(2024-11-04); rpart 4.1.24(2025-01-07); RSQLite 2.3.9(2024-12-03); rsvd 1.0.5(2021-04-16); rvest 1.0.4(2024-02-12); S4Arrays 1.7.3(2025-03-20); S4Vectors 0.45.4(2025-03-20); ScaledMatrix 1.15.0(2025-03-20); scales 1.3.0(2023-11-28); segmented 2.1-4(2025-02-28); sessioninfo 1.2.3(2025-02-05); SingleCellExperiment 1.29.2(2025-03-20); SparseArray 1.7.7(2025-03-20); sparseMatrixStats 1.19.0(2025-03-20); SpatialExperiment 1.17.0(2025-03-20); stringi 1.8.4(2024-05-06); stringr 1.5.1(2023-11-14); SummarizedExperiment 1.37.0(2025-03-20); survival 3.8-3(2024-12-17); testthat 3.2.3(2025-01-13); tibble 3.2.1(2023-03-20); tidyr 1.3.1(2024-01-24); tidyselect 1.2.1(2024-03-11); timechange 0.3.0(2024-01-18); tzdb 0.5.0(2025-03-15); UCSC.utils 1.3.1(2025-03-20); vctrs 0.6.5(2023-12-01); viper 1.41.0(2025-03-20); viridisLite 0.4.2(2023-05-02); waldo 0.6.1(2024-11-07); withr 3.0.2(2024-10-28); xfun 0.51(2025-02-19); XML 3.99-0.18(2025-01-01); xml2 1.3.8(2025-03-14); xtable 1.8-4(2019-04-21); XVector 0.47.2(2025-03-20); yaml 2.3.10(2024-07-26); zip 2.3.2(2025-02-01)
[2025-03-21 05:54:19] [INFO]    [OmnipathR] CURL: version: 8.4.0; headers: 8.4.0; ssl_version: OpenSSL/3.0.12; libz_version: 1.2.13; libssh_version: libssh/0.10.5/openssl/zlib; libidn_version: 2.3.4; host: aarch64-openEuler-linux-gnu; protocols: dict, file, ftp, ftps, gopher, gophers, http, https, imap, imaps, ldap, ldaps, mqtt, pop3, pop3s, rtsp, scp, sftp, smb, smbs, smtp, smtps, telnet, tftp; ipv6: TRUE; http2: TRUE; idn: TRUE; url_parser: TRUE
[2025-03-21 05:54:19] [TRACE]   [OmnipathR] Running on a build server, wiping cache.
[2025-03-21 05:54:19] [TRACE]   [OmnipathR] Cache is at `/home/biocbuild/.cache/OmnipathR`.
[2025-03-21 05:54:19] [TRACE]   [OmnipathR] Contains 8 files.
[2025-03-21 05:54:19] [TRACE]   [OmnipathR] Cache is locked: FALSE.
[2025-03-21 05:54:19] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-21 05:54:19] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-21 05:54:19] [SUCCESS] [OmnipathR] Removing all cache contents from `/home/biocbuild/.cache/OmnipathR`.
[2025-03-21 05:54:19] [TRACE]   [OmnipathR] Pandoc version: `2.12`.
[2025-03-21 05:54:19] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/R/R-devel_2025-02-19/site-library/OmnipathR/db/db_def.json` (encoding: UTF-8).
[2025-03-21 05:54:19] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-21 05:54:19] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/R/R-devel_2025-02-19/site-library/OmnipathR/internal/magic_bytes.json` (encoding: UTF-8).
[2025-03-21 05:54:19] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-21 05:54:19] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/R/R-devel_2025-02-19/site-library/OmnipathR/internal/urls.json` (encoding: UTF-8).
[2025-03-21 05:54:19] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-21 05:54:19] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/R/R-devel_2025-02-19/site-library/OmnipathR/internal/id_types.json` (encoding: UTF-8).
[2025-03-21 05:54:19] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-21 05:54:19] [TRACE]   [OmnipathR] Cache locked: FALSE
[2025-03-21 05:54:20] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-03-21 05:54:20] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-21 05:54:21] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-03-21 05:54:21] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-21 05:54:22] [INFO]    [OmnipathR] Loading database `Ensembl and OMA organism names`.
[2025-03-21 05:54:22] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-21 05:54:22] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-21 05:54:22] [INFO]    [OmnipathR] Looking up in cache `https://www.ensembl.org/info/about/species.html`: key=7332486db7400730697234bad76ca0c8e4d00799, no version available.
[2025-03-21 05:54:22] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-21 05:54:22] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-21 05:54:22] [INFO]    [OmnipathR] Created new version for cache record 7332486db7400730697234bad76ca0c8e4d00799: version 1.
[2025-03-21 05:54:22] [TRACE]   [OmnipathR] Cache file path: /home/biocbuild/.cache/OmnipathR/7332486db7400730697234bad76ca0c8e4d00799-1.html
[2025-03-21 05:54:22] [INFO]    [OmnipathR] Retrieving URL: `https://www.ensembl.org/info/about/species.html`
[2025-03-21 05:54:22] [TRACE]   [OmnipathR] Downloading by `httr2` in `download_base`.
[2025-03-21 05:54:22] [TRACE]   [OmnipathR] Attempt 1/3: `https://www.ensembl.org/info/about/species.html`
[2025-03-21 05:54:22] [TRACE]   [OmnipathR] Preparing httr2 request to URL `https://www.ensembl.org/info/about/species.html`.
[2025-03-21 05:54:22] [TRACE]   [OmnipathR] HTTP headers: [User-Agent=Mozilla/5.0 (X11; Linux x86_64; rv:120.0) Gecko/20100101 Firefox/120.0]
[2025-03-21 05:54:22] [TRACE]   [OmnipathR] The following curl options are not available: tcp_keepcnt
[2025-03-21 05:54:22] [TRACE]   [OmnipathR] Curl options: [connecttimeout=10,timeout=300,debugfunction=<function>,verbose=FALSE,tcp_keepalive=TRUE,tcp_keepintvl=10,tcp_keepidle=10,upkeep_interval_ms=30000,ssl_verifypeer=TRUE,ssl_verifyhost=TRUE]
[2025-03-21 05:54:22] [TRACE]   [OmnipathR] HTTP headers: [User-Agent=Mozilla/5.0 (X11; Linux x86_64; rv:120.0) Gecko/20100101 Firefox/120.0]
[2025-03-21 05:54:22] [TRACE]   [OmnipathR] Sending HTTP request.
[2025-03-21 05:54:23] [TRACE]   [OmnipathR] HTTP 200 (OK)
[2025-03-21 05:54:23] [TRACE]   [OmnipathR] Downloaded 30.9 Kb in 0.896637s from www.ensembl.org (34.5 Kb/s); Redirect: 0.794701s, DNS look up: 0.01969s, Connection: 0.203986s, Pretransfer: 0.577851s, First byte at: 0.895175s
[2025-03-21 05:54:23] [TRACE]   [OmnipathR] Response headers: [content-type=text/html; charset=utf-8,content-length=31666,date=Fri, 21 Mar 2025 05:55:24 GMT,x-nginx-machine=ip-10-25-26-84.ap-southeast-1.compute.internal,server=Apache,set-cookie=redirect_mirror=; path=/; expires=Mon, 01-Jan-2001 00:00:01 GMT,set-cookie=redirect_mirror=no; path=/; expires=Sat, 22 Mar 2025 05:43:50 GMT,set-cookie=ENSEMBL_WWW_SESSION=3ae9be33c3b79de30b74e9f6682c16960c5c10fbd8043cde6c7261fb; path=/; expires=Thu, 31-Dec-2037 23:59:59 GMT; HttpOnly,set-cookie=redirect_mirror=; path=/; expires=Mon, 01-Jan-2001 00:00:01 GMT,set-cookie=redirect_mirror=no; path=/; expires=Sat, 22 Mar 2025 05:43:50 GMT,set-cookie=ENSEMBL_WWW_SESSION=3ae9be33c3b79de30b74e9f6682c16960c5c10fbd8043cde6c7261fb; path=/; expires=Thu, 31-Dec-2037 23:59:59 GMT; HttpOnly,vary=Accept-Encoding,content-encoding=gzip,x-frame-options=SAMEORIGIN,content-security-policy=frame-ancestors 'self',x-cache=Miss from cloudfront,via=1.1 a0fb529982aa9787ef3a5780a065c43a.cloudfront.net (CloudFront),x-amz-cf-pop=SIN2-P4,x-amz-cf-id=Bgl2rI46uQN0pV23hA9qeomLpI9xU1HLTsyq1rz1iDUJiUPEsqTfIA==,vary=Origin]
[2025-03-21 05:54:24] [INFO]    [OmnipathR] Download ready [key=7332486db7400730697234bad76ca0c8e4d00799, version=1]
[2025-03-21 05:54:24] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-21 05:54:24] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-21 05:54:24] [INFO]    [OmnipathR] Cache item `7332486db7400730697234bad76ca0c8e4d00799` version 1: status changed from `unknown` to `ready`.
[2025-03-21 05:54:24] [TRACE]   [OmnipathR] Downloading by `generic_downloader`.
[2025-03-21 05:54:25] [TRACE]   [OmnipathR] Looking up in cache: `https://omabrowser.org/All/oma-species.txt`.
[2025-03-21 05:54:25] [INFO]    [OmnipathR] Cache record does not exist: `https://omabrowser.org/All/oma-species.txt`
[2025-03-21 05:54:25] [TRACE]   [OmnipathR] Could not find in cache, initiating download: `https://omabrowser.org/All/oma-species.txt`.
[2025-03-21 05:54:25] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-21 05:54:25] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-21 05:54:25] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-21 05:54:25] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-21 05:54:25] [INFO]    [OmnipathR] Cache item `30e690cbb55dfc63b5903ab337f34ffc2f4be397` version 1: status changed from `unknown` to `started`.
[2025-03-21 05:54:25] [TRACE]   [OmnipathR] Exporting object to RDS: `/home/biocbuild/.cache/OmnipathR/30e690cbb55dfc63b5903ab337f34ffc2f4be397-1.rds`.
[2025-03-21 05:54:25] [INFO]    [OmnipathR] Retrieving URL: `https://omabrowser.org/All/oma-species.txt`
[2025-03-21 05:54:25] [TRACE]   [OmnipathR] Attempt 1/3: `https://omabrowser.org/All/oma-species.txt`
[2025-03-21 05:54:25] [TRACE]   [OmnipathR] The following curl options are not available: tcp_keepcnt
[2025-03-21 05:54:25] [TRACE]   [OmnipathR] Curl options: [connecttimeout=10,timeout=300,debugfunction=<function>,verbose=FALSE,tcp_keepalive=TRUE,tcp_keepintvl=10,tcp_keepidle=10,upkeep_interval_ms=30000,ssl_verifypeer=TRUE,ssl_verifyhost=TRUE]
[2025-03-21 05:54:27] [TRACE]   [OmnipathR] Downloaded 108 Kb in 1.985727s from omabrowser.org (54.4 Kb/s); Redirect: 0s, DNS look up: 0.009081s, Connection: 0.338237s, Pretransfer: 0.672004s, First byte at: 1.003953s
[2025-03-21 05:54:28] [TRACE]   [OmnipathR] Exported RDS to `/home/biocbuild/.cache/OmnipathR/30e690cbb55dfc63b5903ab337f34ffc2f4be397-1.rds`.
[2025-03-21 05:54:28] [INFO]    [OmnipathR] Download ready [key=30e690cbb55dfc63b5903ab337f34ffc2f4be397, version=1]
[2025-03-21 05:54:28] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-21 05:54:28] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-21 05:54:28] [INFO]    [OmnipathR] Cache item `30e690cbb55dfc63b5903ab337f34ffc2f4be397` version 1: status changed from `started` to `ready`.
[2025-03-21 05:54:28] [INFO]    [OmnipathR] Loaded database `Ensembl and OMA organism names`.
[2025-03-21 05:54:28] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-03-21 05:54:28] [TRACE]   [OmnipathR] Arguments for OmniPath query: [wide=TRUE,resources=TFcensus,query_type=annotations]
[2025-03-21 05:54:28] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-03-21 05:54:28] [TRACE]   [OmnipathR] Orthology targets: 
[2025-03-21 05:54:29] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-03-21 05:54:29] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-21 05:54:29] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/annotations?resources=TFcensus&license=academic`
[2025-03-21 05:54:29] [INFO]    [OmnipathR] Cache record does not exist: `https://omnipathdb.org/annotations?resources=TFcensus&license=academic`
[2025-03-21 05:54:29] [TRACE]   [OmnipathR] Looking up in cache: `http://no-tls.omnipathdb.org/annotations?resources=TFcensus&license=academic`
[2025-03-21 05:54:29] [INFO]    [OmnipathR] Cache record does not exist: `http://no-tls.omnipathdb.org/annotations?resources=TFcensus&license=academic`
[2025-03-21 05:54:29] [TRACE]   [OmnipathR] Attempting `https://omnipathdb.org/annotations?resources=TFcensus&license=academic`
[2025-03-21 05:54:29] [INFO]    [OmnipathR] Retrieving URL: `https://omnipathdb.org/annotations?resources=TFcensus&license=academic`
[2025-03-21 05:54:29] [TRACE]   [OmnipathR] Attempt 1/3: `https://omnipathdb.org/annotations?resources=TFcensus&license=academic`
[2025-03-21 05:54:29] [TRACE]   [OmnipathR] The following curl options are not available: tcp_keepcnt
[2025-03-21 05:54:29] [TRACE]   [OmnipathR] Curl options: [connecttimeout=10,timeout=300,debugfunction=<function>,verbose=FALSE,tcp_keepalive=TRUE,tcp_keepintvl=10,tcp_keepidle=10,upkeep_interval_ms=30000,ssl_verifypeer=TRUE,ssl_verifyhost=TRUE]
[2025-03-21 05:54:30] [TRACE]   [OmnipathR] Downloaded 29.2 Kb in 0.676849s from omnipathdb.org (43.1 Kb/s); Redirect: 0s, DNS look up: 0.000645s, Connection: 0.16743s, Pretransfer: 0.338889s, First byte at: 0.672818s
[2025-03-21 05:54:31] [INFO]    [OmnipathR] Successfully retrieved: `https://omnipathdb.org/annotations?resources=TFcensus&license=academic`
[2025-03-21 05:54:31] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-21 05:54:31] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-21 05:54:31] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-21 05:54:31] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-21 05:54:31] [INFO]    [OmnipathR] Cache item `6f000d9b5edd9832b1c28754d1c3d9449c1c7490` version 1: status changed from `unknown` to `started`.
[2025-03-21 05:54:31] [TRACE]   [OmnipathR] Exporting object to RDS: `/home/biocbuild/.cache/OmnipathR/6f000d9b5edd9832b1c28754d1c3d9449c1c7490-1.rds`.
[2025-03-21 05:54:31] [TRACE]   [OmnipathR] Exported RDS to `/home/biocbuild/.cache/OmnipathR/6f000d9b5edd9832b1c28754d1c3d9449c1c7490-1.rds`.
[2025-03-21 05:54:31] [INFO]    [OmnipathR] Download ready [key=6f000d9b5edd9832b1c28754d1c3d9449c1c7490, version=1]
[2025-03-21 05:54:31] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-21 05:54:31] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-21 05:54:31] [INFO]    [OmnipathR] Cache item `6f000d9b5edd9832b1c28754d1c3d9449c1c7490` version 1: status changed from `started` to `ready`.
[2025-03-21 05:54:31] [SUCCESS] [OmnipathR] Downloaded 3099 annotation records.
[2025-03-21 05:54:32] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-03-21 05:54:32] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-21 05:54:32] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-03-21 05:54:32] [TRACE]   [OmnipathR] Arguments for OmniPath query: [wide=TRUE,resources=PROGENy,query_type=annotations]
[2025-03-21 05:54:32] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-03-21 05:54:32] [TRACE]   [OmnipathR] Orthology targets: 
[2025-03-21 05:54:33] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-03-21 05:54:33] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-21 05:54:33] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/annotations?resources=PROGENy&license=academic`
[2025-03-21 05:54:33] [INFO]    [OmnipathR] Cache record does not exist: `https://omnipathdb.org/annotations?resources=PROGENy&license=academic`
[2025-03-21 05:54:33] [TRACE]   [OmnipathR] Looking up in cache: `http://no-tls.omnipathdb.org/annotations?resources=PROGENy&license=academic`
[2025-03-21 05:54:33] [INFO]    [OmnipathR] Cache record does not exist: `http://no-tls.omnipathdb.org/annotations?resources=PROGENy&license=academic`
[2025-03-21 05:54:33] [TRACE]   [OmnipathR] Attempting `https://omnipathdb.org/annotations?resources=PROGENy&license=academic`
[2025-03-21 05:54:33] [INFO]    [OmnipathR] Retrieving URL: `https://omnipathdb.org/annotations?resources=PROGENy&license=academic`
[2025-03-21 05:54:33] [TRACE]   [OmnipathR] Attempt 1/3: `https://omnipathdb.org/annotations?resources=PROGENy&license=academic`
[2025-03-21 05:54:33] [TRACE]   [OmnipathR] The following curl options are not available: tcp_keepcnt
[2025-03-21 05:54:33] [TRACE]   [OmnipathR] Curl options: [connecttimeout=10,timeout=300,debugfunction=<function>,verbose=FALSE,tcp_keepalive=TRUE,tcp_keepintvl=10,tcp_keepidle=10,upkeep_interval_ms=30000,ssl_verifypeer=TRUE,ssl_verifyhost=TRUE]
[2025-03-21 05:54:42] [TRACE]   [OmnipathR] Downloaded 8.9 Mb in 6.770652s from omnipathdb.org (1.3 Mb/s); Redirect: 0s, DNS look up: 0.002502s, Connection: 0.170771s, Pretransfer: 0.343858s, First byte at: 0.680793s
[2025-03-21 05:54:43] [INFO]    [OmnipathR] Successfully retrieved: `https://omnipathdb.org/annotations?resources=PROGENy&license=academic`
[2025-03-21 05:54:43] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-21 05:54:43] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-21 05:54:43] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-21 05:54:43] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-21 05:54:44] [INFO]    [OmnipathR] Cache item `3492392585ba05414edfae46801492076437d7e7` version 1: status changed from `unknown` to `started`.
[2025-03-21 05:54:44] [TRACE]   [OmnipathR] Exporting object to RDS: `/home/biocbuild/.cache/OmnipathR/3492392585ba05414edfae46801492076437d7e7-1.rds`.
[2025-03-21 05:54:46] [TRACE]   [OmnipathR] Exported RDS to `/home/biocbuild/.cache/OmnipathR/3492392585ba05414edfae46801492076437d7e7-1.rds`.
[2025-03-21 05:54:46] [INFO]    [OmnipathR] Download ready [key=3492392585ba05414edfae46801492076437d7e7, version=1]
[2025-03-21 05:54:46] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-21 05:54:46] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-21 05:54:46] [INFO]    [OmnipathR] Cache item `3492392585ba05414edfae46801492076437d7e7` version 1: status changed from `started` to `ready`.
[2025-03-21 05:54:46] [SUCCESS] [OmnipathR] Downloaded 700239 annotation records.
[2025-03-21 05:54:49] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-03-21 05:54:49] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-21 05:54:49] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-03-21 05:54:49] [TRACE]   [OmnipathR] Arguments for OmniPath query: [wide=TRUE,resources=PROGENy,query_type=annotations]
[2025-03-21 05:54:49] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-03-21 05:54:49] [TRACE]   [OmnipathR] Orthology targets: 
[2025-03-21 05:54:50] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-03-21 05:54:50] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-21 05:54:50] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/annotations?resources=PROGENy&license=academic`
[2025-03-21 05:54:52] [TRACE]   [OmnipathR] Loaded data from RDS `/home/biocbuild/.cache/OmnipathR/3492392585ba05414edfae46801492076437d7e7-1.rds`.
[2025-03-21 05:54:52] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/annotations?resources=PROGENy&license=academic`
[2025-03-21 05:54:52] [SUCCESS] [OmnipathR] Loaded 700239 annotation records from cache.
[2025-03-21 05:54:55] [INFO]    [OmnipathR] Loading database `Orthologous Matrix (OMA) gene pairs`.
[2025-03-21 05:54:55] [TRACE]   [OmnipathR] Downloading by `generic_downloader`.
[2025-03-21 05:54:55] [TRACE]   [OmnipathR] Looking up in cache: `https://omabrowser.org/All/oma-species.txt`.
[2025-03-21 05:54:55] [TRACE]   [OmnipathR] Loaded data from RDS `/home/biocbuild/.cache/OmnipathR/30e690cbb55dfc63b5903ab337f34ffc2f4be397-1.rds`.
[2025-03-21 05:54:55] [TRACE]   [OmnipathR] Downloading by `generic_downloader`.
[2025-03-21 05:54:55] [TRACE]   [OmnipathR] Looking up in cache: `https://omabrowser.org/All/oma-species.txt`.
[2025-03-21 05:54:55] [TRACE]   [OmnipathR] Loaded data from RDS `/home/biocbuild/.cache/OmnipathR/30e690cbb55dfc63b5903ab337f34ffc2f4be397-1.rds`.
[2025-03-21 05:54:55] [TRACE]   [OmnipathR] Downloading by `generic_downloader`.
[2025-03-21 05:54:55] [TRACE]   [OmnipathR] Looking up in cache: `https://omabrowser.org/api/pairs/HUMAN/MOUSE/?format=tsv&xrefs=UniProtKB%2FSwissProt&per_page=2000000`.
[2025-03-21 05:54:55] [INFO]    [OmnipathR] Cache record does not exist: `https://omabrowser.org/api/pairs/HUMAN/MOUSE/?format=tsv&xrefs=UniProtKB%2FSwissProt&per_page=2000000`
[2025-03-21 05:54:55] [TRACE]   [OmnipathR] Could not find in cache, initiating download: `https://omabrowser.org/api/pairs/HUMAN/MOUSE/?format=tsv&xrefs=UniProtKB%2FSwissProt&per_page=2000000`.
[2025-03-21 05:54:55] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-21 05:54:55] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-21 05:54:55] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-21 05:54:55] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-21 05:54:55] [INFO]    [OmnipathR] Cache item `8f45b25c384d814c7de210e7ca40b7e35894e4f1` version 1: status changed from `unknown` to `started`.
[2025-03-21 05:54:55] [TRACE]   [OmnipathR] Exporting object to RDS: `/home/biocbuild/.cache/OmnipathR/8f45b25c384d814c7de210e7ca40b7e35894e4f1-1.rds`.
[2025-03-21 05:54:55] [INFO]    [OmnipathR] Retrieving URL: `https://omabrowser.org/api/pairs/HUMAN/MOUSE/?format=tsv&xrefs=UniProtKB%2FSwissProt&per_page=2000000`
[2025-03-21 05:54:55] [TRACE]   [OmnipathR] Attempt 1/3: `https://omabrowser.org/api/pairs/HUMAN/MOUSE/?format=tsv&xrefs=UniProtKB%2FSwissProt&per_page=2000000`
[2025-03-21 05:54:55] [TRACE]   [OmnipathR] The following curl options are not available: tcp_keepcnt
[2025-03-21 05:54:55] [TRACE]   [OmnipathR] Curl options: [connecttimeout=10,timeout=300,debugfunction=<function>,verbose=FALSE,tcp_keepalive=TRUE,tcp_keepintvl=10,tcp_keepidle=10,upkeep_interval_ms=30000,ssl_verifypeer=TRUE,ssl_verifyhost=TRUE]
[2025-03-21 05:55:22] [TRACE]   [OmnipathR] Downloaded 1.1 Mb in 27.382116s from omabrowser.org (42.3 Kb/s); Redirect: 0s, DNS look up: 0.00082s, Connection: 0.339112s, Pretransfer: 0.68308s, First byte at: 25.354277s
[2025-03-21 05:55:24] [TRACE]   [OmnipathR] Exported RDS to `/home/biocbuild/.cache/OmnipathR/8f45b25c384d814c7de210e7ca40b7e35894e4f1-1.rds`.
[2025-03-21 05:55:24] [INFO]    [OmnipathR] Download ready [key=8f45b25c384d814c7de210e7ca40b7e35894e4f1, version=1]
[2025-03-21 05:55:24] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-21 05:55:24] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-21 05:55:24] [INFO]    [OmnipathR] Cache item `8f45b25c384d814c7de210e7ca40b7e35894e4f1` version 1: status changed from `started` to `ready`.
[2025-03-21 05:55:24] [TRACE]   [OmnipathR] ID translation table: from `uniprot_entry` to `uniprot`, using `uniprot`.
[2025-03-21 05:55:24] [TRACE]   [OmnipathR] Creating ID mapping table from `id` to `accession`, for organism 9606 (only reviewed: TRUE)
[2025-03-21 05:55:24] [TRACE]   [OmnipathR] Loading all UniProt records for organism 9606 (only reviewed: TRUE); fields: id,accession
[2025-03-21 05:55:24] [TRACE]   [OmnipathR] Downloading by `generic_downloader`.
[2025-03-21 05:55:24] [TRACE]   [OmnipathR] Looking up in cache: `https://rest.uniprot.org/uniprotkb/stream?format=tsv&fields=id,accession&query=organism_id:9606%20AND%20reviewed:true`.
[2025-03-21 05:55:24] [INFO]    [OmnipathR] Cache record does not exist: `https://rest.uniprot.org/uniprotkb/stream?format=tsv&fields=id,accession&query=organism_id:9606%20AND%20reviewed:true`
[2025-03-21 05:55:24] [TRACE]   [OmnipathR] Could not find in cache, initiating download: `https://rest.uniprot.org/uniprotkb/stream?format=tsv&fields=id,accession&query=organism_id:9606%20AND%20reviewed:true`.
[2025-03-21 05:55:24] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-21 05:55:24] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-21 05:55:24] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-21 05:55:24] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-21 05:55:24] [INFO]    [OmnipathR] Cache item `6558a1824894a625b8e3f80538cd3aa6e8a44379` version 1: status changed from `unknown` to `started`.
[2025-03-21 05:55:24] [TRACE]   [OmnipathR] Exporting object to RDS: `/home/biocbuild/.cache/OmnipathR/6558a1824894a625b8e3f80538cd3aa6e8a44379-1.rds`.
[2025-03-21 05:55:24] [INFO]    [OmnipathR] Retrieving URL: `https://rest.uniprot.org/uniprotkb/stream?format=tsv&fields=id,accession&query=organism_id:9606%20AND%20reviewed:true`
[2025-03-21 05:55:24] [TRACE]   [OmnipathR] Attempt 1/3: `https://rest.uniprot.org/uniprotkb/stream?format=tsv&fields=id,accession&query=organism_id:9606%20AND%20reviewed:true`
[2025-03-21 05:55:24] [TRACE]   [OmnipathR] The following curl options are not available: tcp_keepcnt
[2025-03-21 05:55:24] [TRACE]   [OmnipathR] Curl options: [connecttimeout=10,timeout=300,debugfunction=<function>,verbose=FALSE,tcp_keepalive=TRUE,tcp_keepintvl=10,tcp_keepidle=10,upkeep_interval_ms=30000,ssl_verifypeer=TRUE,ssl_verifyhost=TRUE]
[2025-03-21 05:56:27] [WARN]    [OmnipathR] Failed to download `https://rest.uniprot.org/uniprotkb/stream?format=tsv&fields=id,accession&query=organism_id:9606%20AND%20reviewed:true` (attempt 1/3); error: Stream error in the HTTP/2 framing layer [rest.uniprot.org]: HTTP/2 stream 1 was not closed cleanly: INTERNAL_ERROR (err 2)
[2025-03-21 05:56:32] [TRACE]   [OmnipathR] Attempt 2/3: `https://rest.uniprot.org/uniprotkb/stream?format=tsv&fields=id,accession&query=organism_id:9606%20AND%20reviewed:true`
[2025-03-21 05:56:32] [TRACE]   [OmnipathR] The following curl options are not available: tcp_keepcnt
[2025-03-21 05:56:32] [TRACE]   [OmnipathR] Curl options: [connecttimeout=10,timeout=300,debugfunction=<function>,verbose=FALSE,tcp_keepalive=TRUE,tcp_keepintvl=10,tcp_keepidle=10,upkeep_interval_ms=30000,ssl_verifypeer=TRUE,ssl_verifyhost=TRUE]
[2025-03-21 05:57:00] [TRACE]   [OmnipathR] Downloaded 128.7 Kb in 27.645954s from rest.uniprot.org (4.7 Kb/s); Redirect: 0s, DNS look up: 0.000908s, Connection: 0.176161s, Pretransfer: 0.531065s, First byte at: 1.254758s
[2025-03-21 05:57:02] [TRACE]   [OmnipathR] Exported RDS to `/home/biocbuild/.cache/OmnipathR/6558a1824894a625b8e3f80538cd3aa6e8a44379-1.rds`.
[2025-03-21 05:57:02] [INFO]    [OmnipathR] Download ready [key=6558a1824894a625b8e3f80538cd3aa6e8a44379, version=1]
[2025-03-21 05:57:02] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-21 05:57:02] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-21 05:57:02] [INFO]    [OmnipathR] Cache item `6558a1824894a625b8e3f80538cd3aa6e8a44379` version 1: status changed from `started` to `ready`.
[2025-03-21 05:57:02] [SUCCESS] [OmnipathR] UniProt (rest.uniprot.org): downloaded 20417 records
[2025-03-21 05:57:02] [TRACE]   [OmnipathR] Translating complexes: 0 complexes in data.
[2025-03-21 05:57:02] [TRACE]   [OmnipathR] 0 complexes after removing the ones mapping to more than 1 items in target identifier space.
[2025-03-21 05:57:02] [TRACE]   [OmnipathR] Translated 0 complexes to 0.
[2025-03-21 05:57:02] [TRACE]   [OmnipathR] 13774 rows before translation, 13774 uniprot_entry IDs in column `id_organism_a`.
[2025-03-21 05:57:02] [TRACE]   [OmnipathR] 13774 rows after translation; translated 13570 `uniprot_entry` IDs in column `id_organism_a` to 13570 `uniprot` IDs in column `id_organism_a`.
[2025-03-21 05:57:02] [TRACE]   [OmnipathR] ID translation table: from `uniprot_entry` to `uniprot`, using `uniprot`.
[2025-03-21 05:57:02] [TRACE]   [OmnipathR] Creating ID mapping table from `id` to `accession`, for organism 10090 (only reviewed: TRUE)
[2025-03-21 05:57:02] [TRACE]   [OmnipathR] Loading all UniProt records for organism 10090 (only reviewed: TRUE); fields: id,accession
[2025-03-21 05:57:02] [TRACE]   [OmnipathR] Downloading by `generic_downloader`.
[2025-03-21 05:57:02] [TRACE]   [OmnipathR] Looking up in cache: `https://rest.uniprot.org/uniprotkb/stream?format=tsv&fields=id,accession&query=organism_id:10090%20AND%20reviewed:true`.
[2025-03-21 05:57:02] [INFO]    [OmnipathR] Cache record does not exist: `https://rest.uniprot.org/uniprotkb/stream?format=tsv&fields=id,accession&query=organism_id:10090%20AND%20reviewed:true`
[2025-03-21 05:57:02] [TRACE]   [OmnipathR] Could not find in cache, initiating download: `https://rest.uniprot.org/uniprotkb/stream?format=tsv&fields=id,accession&query=organism_id:10090%20AND%20reviewed:true`.
[2025-03-21 05:57:02] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-21 05:57:02] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-21 05:57:02] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-21 05:57:02] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-21 05:57:02] [INFO]    [OmnipathR] Cache item `43ea5f2cdaa9ac7e0e114371af97235cdddd776f` version 1: status changed from `unknown` to `started`.
[2025-03-21 05:57:02] [TRACE]   [OmnipathR] Exporting object to RDS: `/home/biocbuild/.cache/OmnipathR/43ea5f2cdaa9ac7e0e114371af97235cdddd776f-1.rds`.
[2025-03-21 05:57:02] [INFO]    [OmnipathR] Retrieving URL: `https://rest.uniprot.org/uniprotkb/stream?format=tsv&fields=id,accession&query=organism_id:10090%20AND%20reviewed:true`
[2025-03-21 05:57:02] [TRACE]   [OmnipathR] Attempt 1/3: `https://rest.uniprot.org/uniprotkb/stream?format=tsv&fields=id,accession&query=organism_id:10090%20AND%20reviewed:true`
[2025-03-21 05:57:02] [TRACE]   [OmnipathR] The following curl options are not available: tcp_keepcnt
[2025-03-21 05:57:02] [TRACE]   [OmnipathR] Curl options: [connecttimeout=10,timeout=300,debugfunction=<function>,verbose=FALSE,tcp_keepalive=TRUE,tcp_keepintvl=10,tcp_keepidle=10,upkeep_interval_ms=30000,ssl_verifypeer=TRUE,ssl_verifyhost=TRUE]
[2025-03-21 05:57:15] [TRACE]   [OmnipathR] Downloaded 110.4 Kb in 12.299343s from rest.uniprot.org (9 Kb/s); Redirect: 0s, DNS look up: 0.006398s, Connection: 0.187983s, Pretransfer: 0.556453s, First byte at: 1.179835s
[2025-03-21 05:57:16] [TRACE]   [OmnipathR] Exported RDS to `/home/biocbuild/.cache/OmnipathR/43ea5f2cdaa9ac7e0e114371af97235cdddd776f-1.rds`.
[2025-03-21 05:57:16] [INFO]    [OmnipathR] Download ready [key=43ea5f2cdaa9ac7e0e114371af97235cdddd776f, version=1]
[2025-03-21 05:57:16] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-21 05:57:16] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-21 05:57:16] [INFO]    [OmnipathR] Cache item `43ea5f2cdaa9ac7e0e114371af97235cdddd776f` version 1: status changed from `started` to `ready`.
[2025-03-21 05:57:16] [SUCCESS] [OmnipathR] UniProt (rest.uniprot.org): downloaded 17228 records
[2025-03-21 05:57:17] [TRACE]   [OmnipathR] Translating complexes: 0 complexes in data.
[2025-03-21 05:57:17] [TRACE]   [OmnipathR] 0 complexes after removing the ones mapping to more than 1 items in target identifier space.
[2025-03-21 05:57:17] [TRACE]   [OmnipathR] Translated 0 complexes to 0.
[2025-03-21 05:57:17] [TRACE]   [OmnipathR] 13774 rows before translation, 13773 uniprot_entry IDs in column `id_organism_b`.
[2025-03-21 05:57:17] [TRACE]   [OmnipathR] 13774 rows after translation; translated 13273 `uniprot_entry` IDs in column `id_organism_b` to 13273 `uniprot` IDs in column `id_organism_b`.
[2025-03-21 05:57:17] [INFO]    [OmnipathR] Loaded database `Orthologous Matrix (OMA) gene pairs`.
[2025-03-21 05:57:17] [TRACE]   [OmnipathR] ID translation table: from `uniprot` to `genesymbol`, using `uniprot`.
[2025-03-21 05:57:17] [TRACE]   [OmnipathR] Creating ID mapping table from `accession` to `gene_primary`, for organism 10090 (only reviewed: TRUE)
[2025-03-21 05:57:17] [TRACE]   [OmnipathR] Loading all UniProt records for organism 10090 (only reviewed: TRUE); fields: accession,gene_primary
[2025-03-21 05:57:17] [TRACE]   [OmnipathR] Downloading by `generic_downloader`.
[2025-03-21 05:57:17] [TRACE]   [OmnipathR] Looking up in cache: `https://rest.uniprot.org/uniprotkb/stream?format=tsv&fields=accession,gene_primary&query=organism_id:10090%20AND%20reviewed:true`.
[2025-03-21 05:57:17] [INFO]    [OmnipathR] Cache record does not exist: `https://rest.uniprot.org/uniprotkb/stream?format=tsv&fields=accession,gene_primary&query=organism_id:10090%20AND%20reviewed:true`
[2025-03-21 05:57:17] [TRACE]   [OmnipathR] Could not find in cache, initiating download: `https://rest.uniprot.org/uniprotkb/stream?format=tsv&fields=accession,gene_primary&query=organism_id:10090%20AND%20reviewed:true`.
[2025-03-21 05:57:17] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-21 05:57:17] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-21 05:57:17] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-21 05:57:17] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-21 05:57:17] [INFO]    [OmnipathR] Cache item `3ec84ba713c02573704adb50f1a94dab684df34b` version 1: status changed from `unknown` to `started`.
[2025-03-21 05:57:17] [TRACE]   [OmnipathR] Exporting object to RDS: `/home/biocbuild/.cache/OmnipathR/3ec84ba713c02573704adb50f1a94dab684df34b-1.rds`.
[2025-03-21 05:57:17] [INFO]    [OmnipathR] Retrieving URL: `https://rest.uniprot.org/uniprotkb/stream?format=tsv&fields=accession,gene_primary&query=organism_id:10090%20AND%20reviewed:true`
[2025-03-21 05:57:17] [TRACE]   [OmnipathR] Attempt 1/3: `https://rest.uniprot.org/uniprotkb/stream?format=tsv&fields=accession,gene_primary&query=organism_id:10090%20AND%20reviewed:true`
[2025-03-21 05:57:17] [TRACE]   [OmnipathR] The following curl options are not available: tcp_keepcnt
[2025-03-21 05:57:17] [TRACE]   [OmnipathR] Curl options: [connecttimeout=10,timeout=300,debugfunction=<function>,verbose=FALSE,tcp_keepalive=TRUE,tcp_keepintvl=10,tcp_keepidle=10,upkeep_interval_ms=30000,ssl_verifypeer=TRUE,ssl_verifyhost=TRUE]
[2025-03-21 05:57:33] [TRACE]   [OmnipathR] Downloaded 110.4 Kb in 15.768646s from rest.uniprot.org (7 Kb/s); Redirect: 0s, DNS look up: 0.000737s, Connection: 0.176195s, Pretransfer: 0.53296s, First byte at: 1.472649s
[2025-03-21 05:57:35] [TRACE]   [OmnipathR] Exported RDS to `/home/biocbuild/.cache/OmnipathR/3ec84ba713c02573704adb50f1a94dab684df34b-1.rds`.
[2025-03-21 05:57:35] [INFO]    [OmnipathR] Download ready [key=3ec84ba713c02573704adb50f1a94dab684df34b, version=1]
[2025-03-21 05:57:35] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-21 05:57:35] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-21 05:57:35] [INFO]    [OmnipathR] Cache item `3ec84ba713c02573704adb50f1a94dab684df34b` version 1: status changed from `started` to `ready`.
[2025-03-21 05:57:35] [SUCCESS] [OmnipathR] UniProt (rest.uniprot.org): downloaded 17228 records
[2025-03-21 05:57:35] [TRACE]   [OmnipathR] Translating complexes: 0 complexes in data.
[2025-03-21 05:57:35] [TRACE]   [OmnipathR] 0 complexes after removing the ones mapping to more than 1 items in target identifier space.
[2025-03-21 05:57:35] [TRACE]   [OmnipathR] Translated 0 complexes to 0.
[2025-03-21 05:57:35] [TRACE]   [OmnipathR] 164184 rows before translation, 12877 uniprot IDs in column `uniprot`.
[2025-03-21 05:57:35] [TRACE]   [OmnipathR] 164184 rows after translation; translated 12877 `uniprot` IDs in column `uniprot` to 12790 `genesymbol` IDs in column `genesymbol`.
[2025-03-21 05:57:36] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-03-21 05:57:36] [TRACE]   [OmnipathR] Arguments for OmniPath query: [dorothea_levels=[A,B,C,D],genesymbols=TRUE,organisms=9606,query_type=interactions,datasets=dorothea]
[2025-03-21 05:57:36] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-03-21 05:57:36] [TRACE]   [OmnipathR] Orthology targets: 
[2025-03-21 05:57:36] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&datasets=dorothea&organisms=9606&dorothea_levels=A,B,C,D&fields=sources,references,curation_effort,dorothea_level&license=academic`
[2025-03-21 05:57:36] [INFO]    [OmnipathR] Cache record does not exist: `https://omnipathdb.org/interactions?genesymbols=yes&datasets=dorothea&organisms=9606&dorothea_levels=A,B,C,D&fields=sources,references,curation_effort,dorothea_level&license=academic`
[2025-03-21 05:57:36] [TRACE]   [OmnipathR] Looking up in cache: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&datasets=dorothea&organisms=9606&dorothea_levels=A,B,C,D&fields=sources,references,curation_effort,dorothea_level&license=academic`
[2025-03-21 05:57:36] [INFO]    [OmnipathR] Cache record does not exist: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&datasets=dorothea&organisms=9606&dorothea_levels=A,B,C,D&fields=sources,references,curation_effort,dorothea_level&license=academic`
[2025-03-21 05:57:36] [TRACE]   [OmnipathR] Attempting `https://omnipathdb.org/interactions?genesymbols=yes&datasets=dorothea&organisms=9606&dorothea_levels=A,B,C,D&fields=sources,references,curation_effort,dorothea_level&license=academic`
[2025-03-21 05:57:36] [INFO]    [OmnipathR] Retrieving URL: `https://omnipathdb.org/interactions?genesymbols=yes&datasets=dorothea&organisms=9606&dorothea_levels=A,B,C,D&fields=sources,references,curation_effort,dorothea_level&license=academic`
[2025-03-21 05:57:36] [TRACE]   [OmnipathR] Attempt 1/3: `https://omnipathdb.org/interactions?genesymbols=yes&datasets=dorothea&organisms=9606&dorothea_levels=A,B,C,D&fields=sources,references,curation_effort,dorothea_level&license=academic`
[2025-03-21 05:57:36] [TRACE]   [OmnipathR] The following curl options are not available: tcp_keepcnt
[2025-03-21 05:57:36] [TRACE]   [OmnipathR] Curl options: [connecttimeout=10,timeout=300,debugfunction=<function>,verbose=FALSE,tcp_keepalive=TRUE,tcp_keepintvl=10,tcp_keepidle=10,upkeep_interval_ms=30000,ssl_verifypeer=TRUE,ssl_verifyhost=TRUE]
[2025-03-21 05:57:40] [TRACE]   [OmnipathR] Downloaded 3.3 Mb in 3.401184s from omnipathdb.org (1001.2 Kb/s); Redirect: 0s, DNS look up: 0.000768s, Connection: 0.167944s, Pretransfer: 0.33852s, First byte at: 0.670364s
[2025-03-21 05:57:42] [INFO]    [OmnipathR] Successfully retrieved: `https://omnipathdb.org/interactions?genesymbols=yes&datasets=dorothea&organisms=9606&dorothea_levels=A,B,C,D&fields=sources,references,curation_effort,dorothea_level&license=academic`
[2025-03-21 05:57:42] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-21 05:57:42] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-21 05:57:42] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-21 05:57:42] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-21 05:57:42] [INFO]    [OmnipathR] Cache item `46d37339bbc3f9a05bb89ccb79278cf1233f5cdf` version 1: status changed from `unknown` to `started`.
[2025-03-21 05:57:42] [TRACE]   [OmnipathR] Exporting object to RDS: `/home/biocbuild/.cache/OmnipathR/46d37339bbc3f9a05bb89ccb79278cf1233f5cdf-1.rds`.
[2025-03-21 05:57:43] [TRACE]   [OmnipathR] Exported RDS to `/home/biocbuild/.cache/OmnipathR/46d37339bbc3f9a05bb89ccb79278cf1233f5cdf-1.rds`.
[2025-03-21 05:57:43] [INFO]    [OmnipathR] Download ready [key=46d37339bbc3f9a05bb89ccb79278cf1233f5cdf, version=1]
[2025-03-21 05:57:43] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-21 05:57:43] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-21 05:57:43] [INFO]    [OmnipathR] Cache item `46d37339bbc3f9a05bb89ccb79278cf1233f5cdf` version 1: status changed from `started` to `ready`.
[2025-03-21 05:57:57] [SUCCESS] [OmnipathR] Downloaded 278830 interactions.
[2025-03-21 05:58:12] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-03-21 05:58:12] [TRACE]   [OmnipathR] Arguments for OmniPath query: [dorothea_levels=[A,B,C,D],genesymbols=TRUE,organisms=10090,query_type=interactions,datasets=dorothea]
[2025-03-21 05:58:12] [TRACE]   [OmnipathR] Organism(s): 10090
[2025-03-21 05:58:12] [TRACE]   [OmnipathR] Orthology targets: 
[2025-03-21 05:58:12] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&datasets=dorothea&organisms=10090&dorothea_levels=A,B,C,D&fields=sources,references,curation_effort,dorothea_level&license=academic`
[2025-03-21 05:58:12] [INFO]    [OmnipathR] Cache record does not exist: `https://omnipathdb.org/interactions?genesymbols=yes&datasets=dorothea&organisms=10090&dorothea_levels=A,B,C,D&fields=sources,references,curation_effort,dorothea_level&license=academic`
[2025-03-21 05:58:12] [TRACE]   [OmnipathR] Looking up in cache: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&datasets=dorothea&organisms=10090&dorothea_levels=A,B,C,D&fields=sources,references,curation_effort,dorothea_level&license=academic`
[2025-03-21 05:58:12] [INFO]    [OmnipathR] Cache record does not exist: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&datasets=dorothea&organisms=10090&dorothea_levels=A,B,C,D&fields=sources,references,curation_effort,dorothea_level&license=academic`
[2025-03-21 05:58:12] [TRACE]   [OmnipathR] Attempting `https://omnipathdb.org/interactions?genesymbols=yes&datasets=dorothea&organisms=10090&dorothea_levels=A,B,C,D&fields=sources,references,curation_effort,dorothea_level&license=academic`
[2025-03-21 05:58:12] [INFO]    [OmnipathR] Retrieving URL: `https://omnipathdb.org/interactions?genesymbols=yes&datasets=dorothea&organisms=10090&dorothea_levels=A,B,C,D&fields=sources,references,curation_effort,dorothea_level&license=academic`
[2025-03-21 05:58:12] [TRACE]   [OmnipathR] Attempt 1/3: `https://omnipathdb.org/interactions?genesymbols=yes&datasets=dorothea&organisms=10090&dorothea_levels=A,B,C,D&fields=sources,references,curation_effort,dorothea_level&license=academic`
[2025-03-21 05:58:12] [TRACE]   [OmnipathR] The following curl options are not available: tcp_keepcnt
[2025-03-21 05:58:12] [TRACE]   [OmnipathR] Curl options: [connecttimeout=10,timeout=300,debugfunction=<function>,verbose=FALSE,tcp_keepalive=TRUE,tcp_keepintvl=10,tcp_keepidle=10,upkeep_interval_ms=30000,ssl_verifypeer=TRUE,ssl_verifyhost=TRUE]
[2025-03-21 05:58:14] [TRACE]   [OmnipathR] Downloaded 2.9 Mb in 1.865193s from omnipathdb.org (1.5 Mb/s); Redirect: 0s, DNS look up: 0.000733s, Connection: 0.16859s, Pretransfer: 0.340858s, First byte at: 0.675154s
[2025-03-21 05:58:16] [INFO]    [OmnipathR] Successfully retrieved: `https://omnipathdb.org/interactions?genesymbols=yes&datasets=dorothea&organisms=10090&dorothea_levels=A,B,C,D&fields=sources,references,curation_effort,dorothea_level&license=academic`
[2025-03-21 05:58:16] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-21 05:58:16] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-21 05:58:16] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-21 05:58:16] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-21 05:58:16] [INFO]    [OmnipathR] Cache item `ff347dedf78ef5e38c9c6d8eed291fa901aa3791` version 1: status changed from `unknown` to `started`.
[2025-03-21 05:58:16] [TRACE]   [OmnipathR] Exporting object to RDS: `/home/biocbuild/.cache/OmnipathR/ff347dedf78ef5e38c9c6d8eed291fa901aa3791-1.rds`.
[2025-03-21 05:58:17] [TRACE]   [OmnipathR] Exported RDS to `/home/biocbuild/.cache/OmnipathR/ff347dedf78ef5e38c9c6d8eed291fa901aa3791-1.rds`.
[2025-03-21 05:58:17] [INFO]    [OmnipathR] Download ready [key=ff347dedf78ef5e38c9c6d8eed291fa901aa3791, version=1]
[2025-03-21 05:58:17] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-21 05:58:17] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-21 05:58:17] [INFO]    [OmnipathR] Cache item `ff347dedf78ef5e38c9c6d8eed291fa901aa3791` version 1: status changed from `started` to `ready`.
[2025-03-21 05:58:29] [SUCCESS] [OmnipathR] Downloaded 234298 interactions.
[2025-03-21 05:58:42] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-03-21 05:58:42] [TRACE]   [OmnipathR] Arguments for OmniPath query: [loops=TRUE,organisms=9606,genesymbols=TRUE,query_type=interactions,datasets=collectri]
[2025-03-21 05:58:42] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-03-21 05:58:42] [TRACE]   [OmnipathR] Orthology targets: 
[2025-03-21 05:58:42] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&datasets=collectri&organisms=9606&fields=sources,references,curation_effort&loops=yes&license=academic`
[2025-03-21 05:58:42] [INFO]    [OmnipathR] Cache record does not exist: `https://omnipathdb.org/interactions?genesymbols=yes&datasets=collectri&organisms=9606&fields=sources,references,curation_effort&loops=yes&license=academic`
[2025-03-21 05:58:42] [TRACE]   [OmnipathR] Looking up in cache: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&datasets=collectri&organisms=9606&fields=sources,references,curation_effort&loops=yes&license=academic`
[2025-03-21 05:58:42] [INFO]    [OmnipathR] Cache record does not exist: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&datasets=collectri&organisms=9606&fields=sources,references,curation_effort&loops=yes&license=academic`
[2025-03-21 05:58:42] [TRACE]   [OmnipathR] Attempting `https://omnipathdb.org/interactions?genesymbols=yes&datasets=collectri&organisms=9606&fields=sources,references,curation_effort&loops=yes&license=academic`
[2025-03-21 05:58:42] [INFO]    [OmnipathR] Retrieving URL: `https://omnipathdb.org/interactions?genesymbols=yes&datasets=collectri&organisms=9606&fields=sources,references,curation_effort&loops=yes&license=academic`
[2025-03-21 05:58:42] [TRACE]   [OmnipathR] Attempt 1/3: `https://omnipathdb.org/interactions?genesymbols=yes&datasets=collectri&organisms=9606&fields=sources,references,curation_effort&loops=yes&license=academic`
[2025-03-21 05:58:42] [TRACE]   [OmnipathR] The following curl options are not available: tcp_keepcnt
[2025-03-21 05:58:42] [TRACE]   [OmnipathR] Curl options: [connecttimeout=10,timeout=300,debugfunction=<function>,verbose=FALSE,tcp_keepalive=TRUE,tcp_keepintvl=10,tcp_keepidle=10,upkeep_interval_ms=30000,ssl_verifypeer=TRUE,ssl_verifyhost=TRUE]
[2025-03-21 05:58:44] [TRACE]   [OmnipathR] Downloaded 1.5 Mb in 1.52518s from omnipathdb.org (977.2 Kb/s); Redirect: 0s, DNS look up: 0.000746s, Connection: 0.167522s, Pretransfer: 0.343378s, First byte at: 0.675334s
[2025-03-21 05:58:45] [INFO]    [OmnipathR] Successfully retrieved: `https://omnipathdb.org/interactions?genesymbols=yes&datasets=collectri&organisms=9606&fields=sources,references,curation_effort&loops=yes&license=academic`
[2025-03-21 05:58:45] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-21 05:58:45] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-21 05:58:45] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-21 05:58:45] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-21 05:58:45] [INFO]    [OmnipathR] Cache item `b10176737ba43d460b13709623189f3911123779` version 1: status changed from `unknown` to `started`.
[2025-03-21 05:58:46] [TRACE]   [OmnipathR] Exporting object to RDS: `/home/biocbuild/.cache/OmnipathR/b10176737ba43d460b13709623189f3911123779-1.rds`.
[2025-03-21 05:58:46] [TRACE]   [OmnipathR] Exported RDS to `/home/biocbuild/.cache/OmnipathR/b10176737ba43d460b13709623189f3911123779-1.rds`.
[2025-03-21 05:58:46] [INFO]    [OmnipathR] Download ready [key=b10176737ba43d460b13709623189f3911123779, version=1]
[2025-03-21 05:58:46] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-21 05:58:46] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-21 05:58:46] [INFO]    [OmnipathR] Cache item `b10176737ba43d460b13709623189f3911123779` version 1: status changed from `started` to `ready`.
[2025-03-21 05:58:49] [SUCCESS] [OmnipathR] Downloaded 64958 interactions.
[2025-03-21 05:58:49] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-03-21 05:58:49] [TRACE]   [OmnipathR] Arguments for OmniPath query: [genesymbols=TRUE,resources=CollecTRI,strict_evidences=TRUE,query_type=interactions,datasets=tf_mirna]
[2025-03-21 05:58:49] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-03-21 05:58:49] [TRACE]   [OmnipathR] Orthology targets: 
[2025-03-21 05:58:50] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-03-21 05:58:50] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-21 05:58:50] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CollecTRI&datasets=tf_mirna&organisms=9606&fields=evidences,sources,references,curation_effort&license=academic`
[2025-03-21 05:58:50] [INFO]    [OmnipathR] Cache record does not exist: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CollecTRI&datasets=tf_mirna&organisms=9606&fields=evidences,sources,references,curation_effort&license=academic`
[2025-03-21 05:58:50] [TRACE]   [OmnipathR] Looking up in cache: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&resources=CollecTRI&datasets=tf_mirna&organisms=9606&fields=evidences,sources,references,curation_effort&license=academic`
[2025-03-21 05:58:50] [INFO]    [OmnipathR] Cache record does not exist: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&resources=CollecTRI&datasets=tf_mirna&organisms=9606&fields=evidences,sources,references,curation_effort&license=academic`
[2025-03-21 05:58:50] [TRACE]   [OmnipathR] Attempting `https://omnipathdb.org/interactions?genesymbols=yes&resources=CollecTRI&datasets=tf_mirna&organisms=9606&fields=evidences,sources,references,curation_effort&license=academic`
[2025-03-21 05:58:50] [INFO]    [OmnipathR] Retrieving URL: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CollecTRI&datasets=tf_mirna&organisms=9606&fields=evidences,sources,references,curation_effort&license=academic`
[2025-03-21 05:58:50] [TRACE]   [OmnipathR] Attempt 1/3: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CollecTRI&datasets=tf_mirna&organisms=9606&fields=evidences,sources,references,curation_effort&license=academic`
[2025-03-21 05:58:50] [TRACE]   [OmnipathR] The following curl options are not available: tcp_keepcnt
[2025-03-21 05:58:50] [TRACE]   [OmnipathR] Curl options: [connecttimeout=10,timeout=300,debugfunction=<function>,verbose=FALSE,tcp_keepalive=TRUE,tcp_keepintvl=10,tcp_keepidle=10,upkeep_interval_ms=30000,ssl_verifypeer=TRUE,ssl_verifyhost=TRUE]
[2025-03-21 05:58:51] [TRACE]   [OmnipathR] Downloaded 9.5 Kb in 0.508105s from omnipathdb.org (18.7 Kb/s); Redirect: 0s, DNS look up: 0.000765s, Connection: 0.166402s, Pretransfer: 0.340196s, First byte at: 0.507797s
[2025-03-21 05:58:53] [INFO]    [OmnipathR] Successfully retrieved: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CollecTRI&datasets=tf_mirna&organisms=9606&fields=evidences,sources,references,curation_effort&license=academic`
[2025-03-21 05:58:53] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-21 05:58:53] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-21 05:58:53] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-21 05:58:53] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-21 05:58:53] [INFO]    [OmnipathR] Cache item `f7d34500401ba98803b7d2b26c48f64cee1eea1b` version 1: status changed from `unknown` to `started`.
[2025-03-21 05:58:53] [TRACE]   [OmnipathR] Exporting object to RDS: `/home/biocbuild/.cache/OmnipathR/f7d34500401ba98803b7d2b26c48f64cee1eea1b-1.rds`.
[2025-03-21 05:58:53] [TRACE]   [OmnipathR] Exported RDS to `/home/biocbuild/.cache/OmnipathR/f7d34500401ba98803b7d2b26c48f64cee1eea1b-1.rds`.
[2025-03-21 05:58:53] [INFO]    [OmnipathR] Download ready [key=f7d34500401ba98803b7d2b26c48f64cee1eea1b, version=1]
[2025-03-21 05:58:53] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-03-21 05:58:53] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-21 05:58:53] [INFO]    [OmnipathR] Cache item `f7d34500401ba98803b7d2b26c48f64cee1eea1b` version 1: status changed from `started` to `ready`.
[2025-03-21 05:58:53] [TRACE]   [OmnipathR] Converting JSON column `evidences` to list.
[2025-03-21 05:58:53] [TRACE]   [OmnipathR] Restricting interaction records to datasets: tf_mirna; and resources: CollecTRI
[2025-03-21 05:58:53] [TRACE]   [OmnipathR] Filtering evidence columns: positive, negative, directed, undirected; to datasets: tf_mirna; and resources: CollecTRI; excluding resources: none
[2025-03-21 05:58:54] [SUCCESS] [OmnipathR] Downloaded 232 interactions.
[2025-03-21 05:58:54] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-03-21 05:58:54] [TRACE]   [OmnipathR] Arguments for OmniPath query: [loops=TRUE,organisms=9606,genesymbols=TRUE,query_type=interactions,datasets=collectri]
[2025-03-21 05:58:54] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-03-21 05:58:54] [TRACE]   [OmnipathR] Orthology targets: 
[2025-03-21 05:58:54] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&datasets=collectri&organisms=9606&fields=sources,references,curation_effort&loops=yes&license=academic`
[2025-03-21 05:58:54] [TRACE]   [OmnipathR] Loaded data from RDS `/home/biocbuild/.cache/OmnipathR/b10176737ba43d460b13709623189f3911123779-1.rds`.
[2025-03-21 05:58:54] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/interactions?genesymbols=yes&datasets=collectri&organisms=9606&fields=sources,references,curation_effort&loops=yes&license=academic`
[2025-03-21 05:58:57] [SUCCESS] [OmnipathR] Loaded 64958 interactions from cache.
[2025-03-21 05:58:57] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-03-21 05:58:57] [TRACE]   [OmnipathR] Arguments for OmniPath query: [genesymbols=TRUE,resources=CollecTRI,strict_evidences=TRUE,query_type=interactions,datasets=tf_mirna]
[2025-03-21 05:58:57] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-03-21 05:58:57] [TRACE]   [OmnipathR] Orthology targets: 
[2025-03-21 05:58:58] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-03-21 05:58:58] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-03-21 05:58:59] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CollecTRI&datasets=tf_mirna&organisms=9606&fields=evidences,sources,references,curation_effort&license=academic`
[2025-03-21 05:58:59] [TRACE]   [OmnipathR] Loaded data from RDS `/home/biocbuild/.cache/OmnipathR/f7d34500401ba98803b7d2b26c48f64cee1eea1b-1.rds`.
[2025-03-21 05:58:59] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CollecTRI&datasets=tf_mirna&organisms=9606&fields=evidences,sources,references,curation_effort&license=academic`
[2025-03-21 05:58:59] [TRACE]   [OmnipathR] Converting JSON column `evidences` to list.
[2025-03-21 05:58:59] [TRACE]   [OmnipathR] Restricting interaction records to datasets: tf_mirna; and resources: CollecTRI
[2025-03-21 05:58:59] [TRACE]   [OmnipathR] Filtering evidence columns: positive, negative, directed, undirected; to datasets: tf_mirna; and resources: CollecTRI; excluding resources: none
[2025-03-21 05:58:59] [SUCCESS] [OmnipathR] Loaded 232 interactions from cache.

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Attaching package: 'dplyr'

The following object is masked from 'package:testthat':

    matches

The following objects are masked from 'package:stats':

    filter, lag

The following objects are masked from 'package:base':

    intersect, setdiff, setequal, union

[ FAIL 1 | WARN 9 | SKIP 0 | PASS 34 ]

══ Failed tests ════════════════════════════════════════════════════════════════
── Failure ('test-statistic-fgsea.R:26:3'): test run_fgsea ─────────────────────
`res_1` (`actual`) not equal to `exp_1` (`expected`).

actual vs expected
                      p_value
  actual[1, ]     0.075479709
  actual[2, ]     0.075479709
- actual[3, ]     0.511687342
+ expected[3, ]   0.548454870
- actual[4, ]     0.511687342
+ expected[4, ]   0.548454870
  actual[5, ]     0.010000000
  actual[6, ]     0.010000000
  actual[7, ]     0.076411558

actual vs expected
                      p_value
  actual[12, ]    0.010000000
  actual[13, ]    0.114238030
  actual[14, ]    0.114238030
- actual[15, ]    0.510665738
+ expected[15, ]  0.522337972
- actual[16, ]    0.510665738
+ expected[16, ]  0.522337972
  actual[17, ]    0.010000000
  actual[18, ]    0.010000000
  actual[19, ]    0.004682543
  actual[20, ]    0.004682543
- actual[21, ]    0.219233595
+ expected[21, ]  0.294730294
and 10 more ...

actual vs expected
                      p_value
  actual[34, ]    1.000000000
  actual[35, ]    0.010000000
  actual[36, ]    0.010000000
- actual[37, ]    0.091542106
+ expected[37, ]  0.103646587
- actual[38, ]    0.091542106
+ expected[38, ]  0.103646587
  actual[39, ]    0.592371428
  actual[40, ]    0.592371428
  actual[41, ]    0.010000000

actual vs expected
                      p_value
  actual[52, ]    0.976649086
  actual[53, ]    0.010000000
  actual[54, ]    0.010000000
- actual[55, ]    0.066624941
+ expected[55, ]  0.076411558
- actual[56, ]    0.066624941
+ expected[56, ]  0.076411558
  actual[57, ]    0.592371428
  actual[58, ]    0.592371428
  actual[59, ]    0.010000000
  actual[60, ]    0.010000000
- actual[61, ]    0.111211902
+ expected[61, ]  0.108185775
and 4 more ...

actual vs expected
                      p_value
  actual[70, ]    1.000000000
  actual[71, ]    0.010000000
  actual[72, ]    0.010000000
- actual[73, ]    0.256981914
+ expected[73, ]  0.469812943
- actual[74, ]    0.256981914
+ expected[74, ]  0.469812943
- actual[75, ]    0.133907888
+ expected[75, ]  0.132394821
- actual[76, ]    0.133907888
+ expected[76, ]  0.132394821
  actual[77, ]    0.123204721
  actual[78, ]    0.123204721
- actual[79, ]    0.146641013
+ expected[79, ]  0.207618744
and 4 more ...

actual vs expected
                      p_value
  actual[88, ]    0.177906190
  actual[89, ]    0.154281338
  actual[90, ]    0.154281338
- actual[91, ]    0.434796297
+ expected[91, ]  0.487321278
- actual[92, ]    0.434796297
+ expected[92, ]  0.487321278
  actual[93, ]    0.009411332
  actual[94, ]    0.009411332
  actual[95, ]    0.005020222
  actual[96, ]    0.005020222
- actual[97, ]    0.294730294
+ expected[97, ]  0.493157392
and 4 more ...

actual vs expected
                      p_value
  actual[106, ]   0.199193619
  actual[107, ]   0.213918294
  actual[108, ]   0.213918294
- actual[109, ]   0.873886766
+ expected[109, ] 0.944265891
- actual[110, ]   0.873886766
+ expected[110, ] 0.944265891
  actual[111, ]   0.187029368
  actual[112, ]   0.187029368
  actual[113, ]   0.180210408

actual vs expected
                      p_value
  actual[118, ]   0.126342554
  actual[119, ]   0.111593916
  actual[120, ]   0.111593916
- actual[121, ]   0.991185346
+ expected[121, ] 1.000000000
- actual[122, ]   0.991185346
+ expected[122, ] 1.000000000
- actual[123, ]   0.123316421
+ expected[123, ] 0.126342554
- actual[124, ]   0.123316421
+ expected[124, ] 0.126342554
  actual[125, ]   0.155922629
  actual[126, ]   0.155922629
  actual[127, ]   0.592371428

actual vs expected
                      p_value
  actual[132, ]   0.124515409
  actual[133, ]   0.592371428
  actual[134, ]   0.592371428
- actual[135, ]   0.174865133
+ expected[135, ] 0.183988307
- actual[136, ]   0.174865133
+ expected[136, ] 0.183988307
  actual[137, ]   0.198360798
  actual[138, ]   0.198360798
  actual[139, ]   0.592371428

  `actual$p_value[1:7]`: 0.075 0.075 0.512 0.512 0.010 0.010 0.076
`expected$p_value[1:7]`: 0.075 0.075 0.548 0.548 0.010 0.010 0.076

     actual$p_value | expected$p_value                
[12] 0.010          | 0.010            [12]           
[13] 0.114          | 0.114            [13]           
[14] 0.114          | 0.114            [14]           
[15] 0.511          - 0.522            [15]           
[16] 0.511          - 0.522            [16]           
[17] 0.010          | 0.010            [17]           
[18] 0.010          | 0.010            [18]           
[19] 0.005          | 0.005            [19]           
[20] 0.005          | 0.005            [20]           
[21] 0.219          - 0.295            [21]           
 ... ...              ...              and 10 more ...

  `actual$p_value[34:41]`: 1.000 0.010 0.010 0.092 0.092 0.592 0.592 0.010
`expected$p_value[34:41]`: 1.000 0.010 0.010 0.104 0.104 0.592 0.592 0.010

     actual$p_value | expected$p_value               
[52] 0.977          | 0.977            [52]          
[53] 0.010          | 0.010            [53]          
[54] 0.010          | 0.010            [54]          
[55] 0.067          - 0.076            [55]          
[56] 0.067          - 0.076            [56]          
[57] 0.592          | 0.592            [57]          
[58] 0.592          | 0.592            [58]          
[59] 0.010          | 0.010            [59]          
[60] 0.010          | 0.010            [60]          
[61] 0.111          - 0.108            [61]          
 ... ...              ...              and 4 more ...

     actual$p_value | expected$p_value               
[70] 1.000          | 1.000            [70]          
[71] 0.010          | 0.010            [71]          
[72] 0.010          | 0.010            [72]          
[73] 0.257          - 0.470            [73]          
[74] 0.257          - 0.470            [74]          
[75] 0.134          - 0.132            [75]          
[76] 0.134          - 0.132            [76]          
[77] 0.123          | 0.123            [77]          
[78] 0.123          | 0.123            [78]          
[79] 0.147          - 0.208            [79]          
 ... ...              ...              and 4 more ...

     actual$p_value | expected$p_value               
[88] 0.178          | 0.178            [88]          
[89] 0.154          | 0.154            [89]          
[90] 0.154          | 0.154            [90]          
[91] 0.435          - 0.487            [91]          
[92] 0.435          - 0.487            [92]          
[93] 0.009          | 0.009            [93]          
[94] 0.009          | 0.009            [94]          
[95] 0.005          | 0.005            [95]          
[96] 0.005          | 0.005            [96]          
[97] 0.295          - 0.493            [97]          
 ... ...              ...              and 4 more ...

  `actual$p_value[106:113]`: 0.199 0.214 0.214 0.874 0.874 0.187 0.187 0.180
`expected$p_value[106:113]`: 0.199 0.214 0.214 0.944 0.944 0.187 0.187 0.180

      actual$p_value | expected$p_value      
[118] 0.126          | 0.126            [118]
[119] 0.112          | 0.112            [119]
[120] 0.112          | 0.112            [120]
[121] 0.991          - 1.000            [121]
[122] 0.991          - 1.000            [122]
[123] 0.123          - 0.126            [123]
[124] 0.123          - 0.126            [124]
[125] 0.156          | 0.156            [125]
[126] 0.156          | 0.156            [126]
[127] 0.592          | 0.592            [127]

  `actual$p_value[132:139]`: 0.125 0.592 0.592 0.175 0.175 0.198 0.198 0.592
`expected$p_value[132:139]`: 0.125 0.592 0.592 0.184 0.184 0.198 0.198 0.592

[ FAIL 1 | WARN 9 | SKIP 0 | PASS 34 ]
Error: Test failures
Execution halted

Example timings

decoupleR.Rcheck/decoupleR-Ex.timings

nameusersystemelapsed
check_corr0.0940.0200.114
convert_f_defaults0.0630.0000.063
decouple0.0010.0000.000
dot-fit_preprocessing0.0290.0000.030
extract_sets0.0300.0000.031
filt_minsize0.0560.0000.056
get_collectri10.358 0.83519.396
get_dorothea31.712 2.39035.866
get_profile_of0.0000.0000.001
get_progeny 7.141 0.49116.706
get_resource1.0480.0713.578
get_toy_data0.0030.0000.004
intersect_regulons0.0410.0010.043
pipe0.0000.0000.001
pivot_wider_profile0.0000.0010.000
randomize_matrix000
rename_net0.0510.0140.068
run_aucell11.160 2.09613.623
run_consensus2.8140.5123.395
run_fgsea25.991 0.78926.914
run_gsva2.2730.5072.876
run_mdt0.2520.0390.295
run_mlm0.1340.0040.141
run_ora0.6540.0450.709
run_udt0.3890.0590.456
run_ulm0.1000.0160.118
run_viper0.9940.2641.294
run_wmean1.0190.0911.131
run_wsum1.0300.1081.159
show_methods0.0650.0120.078
show_resources0.1060.0041.003
tidyeval000