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###
### Running command:
###
###   /Library/Frameworks/R.framework/Resources/bin/R CMD check --install=check:crisprBwa.install-out.txt --library=/Library/Frameworks/R.framework/Resources/library --no-vignettes --timings crisprBwa_1.4.0.tar.gz
###
##############################################################################
##############################################################################


* using log directory ‘/Users/biocbuild/bbs-3.17-bioc-mac-arm64/meat/crisprBwa.Rcheck’
* using R version 4.3.1 (2023-06-16)
* using platform: aarch64-apple-darwin20 (64-bit)
* R was compiled by
    Apple clang version 14.0.0 (clang-1400.0.29.202)
    GNU Fortran (GCC) 12.2.0
* running under: macOS Monterey 12.6.7
* using session charset: UTF-8
* using option ‘--no-vignettes’
* checking for file ‘crisprBwa/DESCRIPTION’ ... OK
* this is package ‘crisprBwa’ version ‘1.4.0’
* package encoding: UTF-8
* checking package namespace information ... OK
* checking package dependencies ... OK
* checking if this is a source package ... OK
* checking if there is a namespace ... OK
* checking for hidden files and directories ... NOTE
Found the following hidden files and directories:
  .BBSoptions
These were most likely included in error. See section ‘Package
structure’ in the ‘Writing R Extensions’ manual.
* checking for portable file names ... OK
* checking for sufficient/correct file permissions ... OK
* checking whether package ‘crisprBwa’ can be installed ... OK
* checking installed package size ... OK
* checking package directory ... OK
* checking ‘build’ directory ... OK
* checking DESCRIPTION meta-information ... OK
* checking top-level files ... OK
* checking for left-over files ... OK
* checking index information ... OK
* checking package subdirectories ... OK
* checking R files for non-ASCII characters ... OK
* checking R files for syntax errors ... OK
* checking whether the package can be loaded ... OK
* checking whether the package can be loaded with stated dependencies ... OK
* checking whether the package can be unloaded cleanly ... OK
* checking whether the namespace can be loaded with stated dependencies ... OK
* checking whether the namespace can be unloaded cleanly ... OK
* checking dependencies in R code ... OK
* checking S3 generic/method consistency ... OK
* checking replacement functions ... OK
* checking foreign function calls ... OK
* checking R code for possible problems ... OK
* checking Rd files ... OK
* checking Rd metadata ... OK
* checking Rd cross-references ... OK
* checking for missing documentation entries ... OK
* checking for code/documentation mismatches ... OK
* checking Rd \usage sections ... OK
* checking Rd contents ... OK
* checking for unstated dependencies in examples ... OK
* checking files in ‘vignettes’ ... OK
* checking examples ... OK
* checking for unstated dependencies in ‘tests’ ... OK
* checking tests ...
  Running ‘testthat.R’
 OK
* checking for unstated dependencies in vignettes ... OK
* checking package vignettes in ‘inst/doc’ ... OK
* checking running R code from vignettes ... SKIPPED
* checking re-building of vignette outputs ... SKIPPED
* checking PDF version of manual ... OK
* DONE

Status: 1 NOTE
See
  ‘/Users/biocbuild/bbs-3.17-bioc-mac-arm64/meat/crisprBwa.Rcheck/00check.log’
for details.

##############################################################################
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###
### Running command:
###
###   /Library/Frameworks/R.framework/Resources/bin/R CMD INSTALL crisprBwa
###
##############################################################################
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* installing to library ‘/Library/Frameworks/R.framework/Versions/4.3-arm64/Resources/library’
* installing *source* package ‘crisprBwa’ ...
** using staged installation
** R
** inst
** byte-compile and prepare package for lazy loading
** help
*** installing help indices
** building package indices
** installing vignettes
** testing if installed package can be loaded from temporary location
** testing if installed package can be loaded from final location
** testing if installed package keeps a record of temporary installation path
* DONE (crisprBwa)

R version 4.3.1 (2023-06-16) -- "Beagle Scouts"
Copyright (C) 2023 The R Foundation for Statistical Computing
Platform: aarch64-apple-darwin20 (64-bit)

R is free software and comes with ABSOLUTELY NO WARRANTY.
You are welcome to redistribute it under certain conditions.
Type 'license()' or 'licence()' for distribution details.

R is a collaborative project with many contributors.
Type 'contributors()' for more information and
'citation()' on how to cite R or R packages in publications.

Type 'demo()' for some demos, 'help()' for on-line help, or
'help.start()' for an HTML browser interface to help.
Type 'q()' to quit R.

> library(testthat)
> library(crisprBwa)
> 
> test_check("crisprBwa")
[bwa_index] Pack FASTA... 0.00 sec
[bwa_index] Construct BWT for the packed sequence...
[bwa_index] 0.04 seconds elapse.
[bwa_index] Update BWT... 0.00 sec
[bwa_index] Pack forward-only FASTA... 0.00 sec
[bwa_index] Construct SA from BWT and Occ... 0.01 sec
[main] Version: 0.7.17-r1198-dirty
[main] CMD: /Library/Frameworks/R.framework/Versions/4.3-arm64/Resources/library/Rbwa/bwa index -p /tmp/RtmpioJslR/chr12 /Library/Frameworks/R.framework/Versions/4.3-arm64/Resources/library/crisprBwa/example/chr12.fa
[main] Real time: 0.095 sec; CPU: 0.069 sec
[bwa_aln_core] calculate SA coordinate... 0.00 sec
[bwa_aln_core] write to the disk... 0.00 sec
[bwa_aln_core] 3 sequences have been processed.
[main] Version: 0.7.17-r1198-dirty
[main] CMD: /Library/Frameworks/R.framework/Versions/4.3-arm64/Resources/library/Rbwa/bwa aln -N -n 0 -l 36 -o 0 /tmp/RtmpioJslR/chr12 /tmp/RtmpioJslR/file16f422e3810b3
[main] Real time: 0.028 sec; CPU: 0.016 sec
[bwa_aln_core] convert to sequence coordinate... 0.00 sec
[bwa_aln_core] refine gapped alignments... 0.00 sec
[bwa_aln_core] print alignments... 0.00 sec
[bwa_aln_core] 3 sequences have been processed.
[main] Version: 0.7.17-r1198-dirty
[main] CMD: /Library/Frameworks/R.framework/Versions/4.3-arm64/Resources/library/Rbwa/bwa samse -n 1000000000 /tmp/RtmpioJslR/chr12 /tmp/RtmpioJslR/file16f422e3810b3.sai /tmp/RtmpioJslR/file16f422e3810b3
[main] Real time: 0.026 sec; CPU: 0.016 sec
[bwa_aln_core] calculate SA coordinate... 0.00 sec
[bwa_aln_core] write to the disk... 0.00 sec
[bwa_aln_core] 3 sequences have been processed.
[main] Version: 0.7.17-r1198-dirty
[main] CMD: /Library/Frameworks/R.framework/Versions/4.3-arm64/Resources/library/Rbwa/bwa aln -N -n 1 -l 36 -o 0 /tmp/RtmpioJslR/chr12 /tmp/RtmpioJslR/file16f4262d06f79
[main] Real time: 0.034 sec; CPU: 0.017 sec
[bwa_aln_core] convert to sequence coordinate... 0.00 sec
[bwa_aln_core] refine gapped alignments... 0.00 sec
[bwa_aln_core] print alignments... 0.00 sec
[bwa_aln_core] 3 sequences have been processed.
[main] Version: 0.7.17-r1198-dirty
[main] CMD: /Library/Frameworks/R.framework/Versions/4.3-arm64/Resources/library/Rbwa/bwa samse -n 1000000000 /tmp/RtmpioJslR/chr12 /tmp/RtmpioJslR/file16f4262d06f79.sai /tmp/RtmpioJslR/file16f4262d06f79
[main] Real time: 0.035 sec; CPU: 0.017 sec
[bwa_aln_core] calculate SA coordinate... 0.00 sec
[bwa_aln_core] write to the disk... 0.00 sec
[bwa_aln_core] 3 sequences have been processed.
[main] Version: 0.7.17-r1198-dirty
[main] CMD: /Library/Frameworks/R.framework/Versions/4.3-arm64/Resources/library/Rbwa/bwa aln -N -n 2 -l 36 -o 0 /tmp/RtmpioJslR/chr12 /tmp/RtmpioJslR/file16f426246a39d
[main] Real time: 0.029 sec; CPU: 0.017 sec
[bwa_aln_core] convert to sequence coordinate... 0.00 sec
[bwa_aln_core] refine gapped alignments... 0.00 sec
[bwa_aln_core] print alignments... 0.00 sec
[bwa_aln_core] 3 sequences have been processed.
[main] Version: 0.7.17-r1198-dirty
[main] CMD: /Library/Frameworks/R.framework/Versions/4.3-arm64/Resources/library/Rbwa/bwa samse -n 1000000000 /tmp/RtmpioJslR/chr12 /tmp/RtmpioJslR/file16f426246a39d.sai /tmp/RtmpioJslR/file16f426246a39d
[main] Real time: 0.030 sec; CPU: 0.016 sec
[bwa_aln_core] calculate SA coordinate... 0.00 sec
[bwa_aln_core] write to the disk... 0.00 sec
[bwa_aln_core] 3 sequences have been processed.
[main] Version: 0.7.17-r1198-dirty
[main] CMD: /Library/Frameworks/R.framework/Versions/4.3-arm64/Resources/library/Rbwa/bwa aln -N -n 3 -l 36 -o 0 /tmp/RtmpioJslR/chr12 /tmp/RtmpioJslR/file16f42b9fcad3
[main] Real time: 0.034 sec; CPU: 0.020 sec
[bwa_aln_core] convert to sequence coordinate... 0.00 sec
[bwa_aln_core] refine gapped alignments... 0.00 sec
[bwa_aln_core] print alignments... 0.00 sec
[bwa_aln_core] 3 sequences have been processed.
[main] Version: 0.7.17-r1198-dirty
[main] CMD: /Library/Frameworks/R.framework/Versions/4.3-arm64/Resources/library/Rbwa/bwa samse -n 1000000000 /tmp/RtmpioJslR/chr12 /tmp/RtmpioJslR/file16f42b9fcad3.sai /tmp/RtmpioJslR/file16f42b9fcad3
[main] Real time: 0.030 sec; CPU: 0.017 sec
[bwa_aln_core] calculate SA coordinate... 0.00 sec
[bwa_aln_core] write to the disk... 0.00 sec
[bwa_aln_core] 1 sequences have been processed.
[main] Version: 0.7.17-r1198-dirty
[main] CMD: /Library/Frameworks/R.framework/Versions/4.3-arm64/Resources/library/Rbwa/bwa aln -N -n 0 -l 144 -o 0 /tmp/RtmpioJslR/chr12 /tmp/RtmpioJslR/file16f4227bce89b
[main] Real time: 0.028 sec; CPU: 0.015 sec
[bwa_aln_core] convert to sequence coordinate... 0.00 sec
[bwa_aln_core] refine gapped alignments... 0.00 sec
[bwa_aln_core] print alignments... 0.00 sec
[bwa_aln_core] 1 sequences have been processed.
[main] Version: 0.7.17-r1198-dirty
[main] CMD: /Library/Frameworks/R.framework/Versions/4.3-arm64/Resources/library/Rbwa/bwa samse -n 1000000000 /tmp/RtmpioJslR/chr12 /tmp/RtmpioJslR/file16f4227bce89b.sai /tmp/RtmpioJslR/file16f4227bce89b
[main] Real time: 0.027 sec; CPU: 0.015 sec
[bwa_index] Pack FASTA... 0.00 sec
[bwa_index] Construct BWT for the packed sequence...
[bwa_index] 0.04 seconds elapse.
[bwa_index] Update BWT... 0.00 sec
[bwa_index] Pack forward-only FASTA... 0.00 sec
[bwa_index] Construct SA from BWT and Occ... 0.01 sec
[main] Version: 0.7.17-r1198-dirty
[main] CMD: /Library/Frameworks/R.framework/Versions/4.3-arm64/Resources/library/Rbwa/bwa index -p /tmp/RtmpioJslR/chr12 /Library/Frameworks/R.framework/Versions/4.3-arm64/Resources/library/crisprBwa/example/chr12.fa
[main] Real time: 0.101 sec; CPU: 0.069 sec
[runCrisprBwa] Using BSgenome.Hsapiens.UCSC.hg38 
[runCrisprBwa] Searching for SpCas9 protospacers 
[bwa_aln_core] calculate SA coordinate... 0.00 sec
[bwa_aln_core] write to the disk... 0.00 sec
[bwa_aln_core] 5 sequences have been processed.
[main] Version: 0.7.17-r1198-dirty
[main] CMD: /Library/Frameworks/R.framework/Versions/4.3-arm64/Resources/library/Rbwa/bwa aln -N -n 0 -l 60 -o 0 /tmp/RtmpioJslR/chr12 /tmp/RtmpioJslR/file16f42634b2c7e
[main] Real time: 0.028 sec; CPU: 0.016 sec
[bwa_aln_core] convert to sequence coordinate... 0.00 sec
[bwa_aln_core] refine gapped alignments... 0.00 sec
[bwa_aln_core] print alignments... 0.00 sec
[bwa_aln_core] 5 sequences have been processed.
[main] Version: 0.7.17-r1198-dirty
[main] CMD: /Library/Frameworks/R.framework/Versions/4.3-arm64/Resources/library/Rbwa/bwa samse -n 1000000000 /tmp/RtmpioJslR/chr12 /tmp/RtmpioJslR/file16f42634b2c7e.sai /tmp/RtmpioJslR/file16f42634b2c7e
[main] Real time: 0.033 sec; CPU: 0.017 sec
[runCrisprBwa] Using BSgenome.Hsapiens.UCSC.hg38 
[runCrisprBwa] Searching for SpCas9 protospacers 
[bwa_aln_core] calculate SA coordinate... 0.00 sec
[bwa_aln_core] write to the disk... 0.00 sec
[bwa_aln_core] 5 sequences have been processed.
[main] Version: 0.7.17-r1198-dirty
[main] CMD: /Library/Frameworks/R.framework/Versions/4.3-arm64/Resources/library/Rbwa/bwa aln -N -n 1 -l 60 -o 0 /tmp/RtmpioJslR/chr12 /tmp/RtmpioJslR/file16f425c56371f
[main] Real time: 0.030 sec; CPU: 0.015 sec
[bwa_aln_core] convert to sequence coordinate... 0.00 sec
[bwa_aln_core] refine gapped alignments... 0.00 sec
[bwa_aln_core] print alignments... 0.00 sec
[bwa_aln_core] 5 sequences have been processed.
[main] Version: 0.7.17-r1198-dirty
[main] CMD: /Library/Frameworks/R.framework/Versions/4.3-arm64/Resources/library/Rbwa/bwa samse -n 1000000000 /tmp/RtmpioJslR/chr12 /tmp/RtmpioJslR/file16f425c56371f.sai /tmp/RtmpioJslR/file16f425c56371f
[main] Real time: 0.025 sec; CPU: 0.016 sec
[runCrisprBwa] Using BSgenome.Hsapiens.UCSC.hg38 
[runCrisprBwa] Searching for SpCas9 protospacers 
[bwa_aln_core] calculate SA coordinate... 0.00 sec
[bwa_aln_core] write to the disk... 0.00 sec
[bwa_aln_core] 5 sequences have been processed.
[main] Version: 0.7.17-r1198-dirty
[main] CMD: /Library/Frameworks/R.framework/Versions/4.3-arm64/Resources/library/Rbwa/bwa aln -N -n 2 -l 60 -o 0 /tmp/RtmpioJslR/chr12 /tmp/RtmpioJslR/file16f42203d0395
[main] Real time: 0.027 sec; CPU: 0.016 sec
[bwa_aln_core] convert to sequence coordinate... 0.00 sec
[bwa_aln_core] refine gapped alignments... 0.00 sec
[bwa_aln_core] print alignments... 0.00 sec
[bwa_aln_core] 5 sequences have been processed.
[main] Version: 0.7.17-r1198-dirty
[main] CMD: /Library/Frameworks/R.framework/Versions/4.3-arm64/Resources/library/Rbwa/bwa samse -n 1000000000 /tmp/RtmpioJslR/chr12 /tmp/RtmpioJslR/file16f42203d0395.sai /tmp/RtmpioJslR/file16f42203d0395
[main] Real time: 0.025 sec; CPU: 0.015 sec
[runCrisprBwa] Using BSgenome.Hsapiens.UCSC.hg38 
[runCrisprBwa] Searching for SpCas9 protospacers 
[bwa_aln_core] calculate SA coordinate... 0.00 sec
[bwa_aln_core] write to the disk... 0.00 sec
[bwa_aln_core] 5 sequences have been processed.
[main] Version: 0.7.17-r1198-dirty
[main] CMD: /Library/Frameworks/R.framework/Versions/4.3-arm64/Resources/library/Rbwa/bwa aln -N -n 3 -l 60 -o 0 /tmp/RtmpioJslR/chr12 /tmp/RtmpioJslR/file16f425b63bbc
[main] Real time: 0.026 sec; CPU: 0.016 sec
[bwa_aln_core] convert to sequence coordinate... 0.00 sec
[bwa_aln_core] refine gapped alignments... 0.00 sec
[bwa_aln_core] print alignments... 0.00 sec
[bwa_aln_core] 5 sequences have been processed.
[main] Version: 0.7.17-r1198-dirty
[main] CMD: /Library/Frameworks/R.framework/Versions/4.3-arm64/Resources/library/Rbwa/bwa samse -n 1000000000 /tmp/RtmpioJslR/chr12 /tmp/RtmpioJslR/file16f425b63bbc.sai /tmp/RtmpioJslR/file16f425b63bbc
[main] Real time: 0.026 sec; CPU: 0.016 sec
[runCrisprBwa] Using BSgenome.Hsapiens.UCSC.hg38 
[runCrisprBwa] Searching for SpCas9 protospacers 
[bwa_aln_core] calculate SA coordinate... 0.00 sec
[bwa_aln_core] write to the disk... 0.00 sec
[bwa_aln_core] 5 sequences have been processed.
[main] Version: 0.7.17-r1198-dirty
[main] CMD: /Library/Frameworks/R.framework/Versions/4.3-arm64/Resources/library/Rbwa/bwa aln -N -n 0 -l 60 -o 0 /tmp/RtmpioJslR/chr12 /tmp/RtmpioJslR/file16f427f0bb691
[main] Real time: 0.032 sec; CPU: 0.016 sec
[bwa_aln_core] convert to sequence coordinate... 0.00 sec
[bwa_aln_core] refine gapped alignments... 0.00 sec
[bwa_aln_core] print alignments... 0.00 sec
[bwa_aln_core] 5 sequences have been processed.
[main] Version: 0.7.17-r1198-dirty
[main] CMD: /Library/Frameworks/R.framework/Versions/4.3-arm64/Resources/library/Rbwa/bwa samse -n 1000000000 /tmp/RtmpioJslR/chr12 /tmp/RtmpioJslR/file16f427f0bb691.sai /tmp/RtmpioJslR/file16f427f0bb691
[main] Real time: 0.027 sec; CPU: 0.016 sec
[runCrisprBwa] Using BSgenome.Hsapiens.UCSC.hg38 
[runCrisprBwa] Searching for SpCas9 protospacers 
[bwa_aln_core] calculate SA coordinate... 0.00 sec
[bwa_aln_core] write to the disk... 0.00 sec
[bwa_aln_core] 5 sequences have been processed.
[main] Version: 0.7.17-r1198-dirty
[main] CMD: /Library/Frameworks/R.framework/Versions/4.3-arm64/Resources/library/Rbwa/bwa aln -N -n 1 -l 60 -o 0 /tmp/RtmpioJslR/chr12 /tmp/RtmpioJslR/file16f4259ff2ac0
[main] Real time: 0.026 sec; CPU: 0.016 sec
[bwa_aln_core] convert to sequence coordinate... 0.00 sec
[bwa_aln_core] refine gapped alignments... 0.00 sec
[bwa_aln_core] print alignments... 0.00 sec
[bwa_aln_core] 5 sequences have been processed.
[main] Version: 0.7.17-r1198-dirty
[main] CMD: /Library/Frameworks/R.framework/Versions/4.3-arm64/Resources/library/Rbwa/bwa samse -n 1000000000 /tmp/RtmpioJslR/chr12 /tmp/RtmpioJslR/file16f4259ff2ac0.sai /tmp/RtmpioJslR/file16f4259ff2ac0
[main] Real time: 0.027 sec; CPU: 0.017 sec
[runCrisprBwa] Using BSgenome.Hsapiens.UCSC.hg38 
[runCrisprBwa] Searching for SpCas9 protospacers 
[bwa_aln_core] calculate SA coordinate... 0.00 sec
[bwa_aln_core] write to the disk... 0.00 sec
[bwa_aln_core] 5 sequences have been processed.
[main] Version: 0.7.17-r1198-dirty
[main] CMD: /Library/Frameworks/R.framework/Versions/4.3-arm64/Resources/library/Rbwa/bwa aln -N -n 2 -l 60 -o 0 /tmp/RtmpioJslR/chr12 /tmp/RtmpioJslR/file16f427f4fd168
[main] Real time: 0.024 sec; CPU: 0.016 sec
[bwa_aln_core] convert to sequence coordinate... 0.00 sec
[bwa_aln_core] refine gapped alignments... 0.00 sec
[bwa_aln_core] print alignments... 0.00 sec
[bwa_aln_core] 5 sequences have been processed.
[main] Version: 0.7.17-r1198-dirty
[main] CMD: /Library/Frameworks/R.framework/Versions/4.3-arm64/Resources/library/Rbwa/bwa samse -n 1000000000 /tmp/RtmpioJslR/chr12 /tmp/RtmpioJslR/file16f427f4fd168.sai /tmp/RtmpioJslR/file16f427f4fd168
[main] Real time: 0.025 sec; CPU: 0.016 sec
[runCrisprBwa] Using BSgenome.Hsapiens.UCSC.hg38 
[runCrisprBwa] Searching for SpCas9 protospacers 
[bwa_aln_core] calculate SA coordinate... 0.00 sec
[bwa_aln_core] write to the disk... 0.00 sec
[bwa_aln_core] 5 sequences have been processed.
[main] Version: 0.7.17-r1198-dirty
[main] CMD: /Library/Frameworks/R.framework/Versions/4.3-arm64/Resources/library/Rbwa/bwa aln -N -n 3 -l 60 -o 0 /tmp/RtmpioJslR/chr12 /tmp/RtmpioJslR/file16f42513d4424
[main] Real time: 0.030 sec; CPU: 0.016 sec
[bwa_aln_core] convert to sequence coordinate... 0.00 sec
[bwa_aln_core] refine gapped alignments... 0.00 sec
[bwa_aln_core] print alignments... 0.00 sec
[bwa_aln_core] 5 sequences have been processed.
[main] Version: 0.7.17-r1198-dirty
[main] CMD: /Library/Frameworks/R.framework/Versions/4.3-arm64/Resources/library/Rbwa/bwa samse -n 1000000000 /tmp/RtmpioJslR/chr12 /tmp/RtmpioJslR/file16f42513d4424.sai /tmp/RtmpioJslR/file16f42513d4424
[main] Real time: 0.027 sec; CPU: 0.016 sec
[runCrisprBwa] Using BSgenome.Hsapiens.UCSC.hg38 
[runCrisprBwa] Searching for SpCas9 protospacers 
[runCrisprBwa] Using BSgenome.Hsapiens.UCSC.hg38 
[runCrisprBwa] Searching for SpCas9 protospacers 
[bwa_aln_core] calculate SA coordinate... 0.00 sec
[bwa_aln_core] write to the disk... 0.00 sec
[bwa_aln_core] 5 sequences have been processed.
[main] Version: 0.7.17-r1198-dirty
[main] CMD: /Library/Frameworks/R.framework/Versions/4.3-arm64/Resources/library/Rbwa/bwa aln -N -n 3 -l 51 -o 0 /tmp/RtmpioJslR/chr12 /tmp/RtmpioJslR/file16f42d44c127
[main] Real time: 0.026 sec; CPU: 0.016 sec
[bwa_aln_core] convert to sequence coordinate... 0.00 sec
[bwa_aln_core] refine gapped alignments... 0.00 sec
[bwa_aln_core] print alignments... 0.00 sec
[bwa_aln_core] 5 sequences have been processed.
[main] Version: 0.7.17-r1198-dirty
[main] CMD: /Library/Frameworks/R.framework/Versions/4.3-arm64/Resources/library/Rbwa/bwa samse -n 1000000000 /tmp/RtmpioJslR/chr12 /tmp/RtmpioJslR/file16f42d44c127.sai /tmp/RtmpioJslR/file16f42d44c127
[main] Real time: 0.034 sec; CPU: 0.016 sec
[runCrisprBwa] Using BSgenome.Hsapiens.UCSC.hg38 
[runCrisprBwa] Searching for AsCas12a protospacers 
[bwa_aln_core] calculate SA coordinate... 0.00 sec
[bwa_aln_core] write to the disk... 0.00 sec
[bwa_aln_core] 4 sequences have been processed.
[main] Version: 0.7.17-r1198-dirty
[main] CMD: /Library/Frameworks/R.framework/Versions/4.3-arm64/Resources/library/Rbwa/bwa aln -N -n 0 -l 69 -o 0 /tmp/RtmpioJslR/chr12 /tmp/RtmpioJslR/file16f421ce4ee3f
[main] Real time: 0.025 sec; CPU: 0.016 sec
[bwa_aln_core] convert to sequence coordinate... 0.00 sec
[bwa_aln_core] refine gapped alignments... 0.00 sec
[bwa_aln_core] print alignments... 0.00 sec
[bwa_aln_core] 4 sequences have been processed.
[main] Version: 0.7.17-r1198-dirty
[main] CMD: /Library/Frameworks/R.framework/Versions/4.3-arm64/Resources/library/Rbwa/bwa samse -n 1000000000 /tmp/RtmpioJslR/chr12 /tmp/RtmpioJslR/file16f421ce4ee3f.sai /tmp/RtmpioJslR/file16f421ce4ee3f
[main] Real time: 0.028 sec; CPU: 0.016 sec
[runCrisprBwa] Using BSgenome.Hsapiens.UCSC.hg38 
[runCrisprBwa] Searching for AsCas12a protospacers 
[bwa_aln_core] calculate SA coordinate... 0.00 sec
[bwa_aln_core] write to the disk... 0.00 sec
[bwa_aln_core] 4 sequences have been processed.
[main] Version: 0.7.17-r1198-dirty
[main] CMD: /Library/Frameworks/R.framework/Versions/4.3-arm64/Resources/library/Rbwa/bwa aln -N -n 1 -l 69 -o 0 /tmp/RtmpioJslR/chr12 /tmp/RtmpioJslR/file16f4279d578ea
[main] Real time: 0.028 sec; CPU: 0.016 sec
[bwa_aln_core] convert to sequence coordinate... 0.00 sec
[bwa_aln_core] refine gapped alignments... 0.00 sec
[bwa_aln_core] print alignments... 0.00 sec
[bwa_aln_core] 4 sequences have been processed.
[main] Version: 0.7.17-r1198-dirty
[main] CMD: /Library/Frameworks/R.framework/Versions/4.3-arm64/Resources/library/Rbwa/bwa samse -n 1000000000 /tmp/RtmpioJslR/chr12 /tmp/RtmpioJslR/file16f4279d578ea.sai /tmp/RtmpioJslR/file16f4279d578ea
[main] Real time: 0.026 sec; CPU: 0.016 sec
[runCrisprBwa] Using BSgenome.Hsapiens.UCSC.hg38 
[runCrisprBwa] Searching for AsCas12a protospacers 
[bwa_aln_core] calculate SA coordinate... 0.00 sec
[bwa_aln_core] write to the disk... 0.00 sec
[bwa_aln_core] 4 sequences have been processed.
[main] Version: 0.7.17-r1198-dirty
[main] CMD: /Library/Frameworks/R.framework/Versions/4.3-arm64/Resources/library/Rbwa/bwa aln -N -n 2 -l 69 -o 0 /tmp/RtmpioJslR/chr12 /tmp/RtmpioJslR/file16f422df58923
[main] Real time: 0.027 sec; CPU: 0.016 sec
[bwa_aln_core] convert to sequence coordinate... 0.00 sec
[bwa_aln_core] refine gapped alignments... 0.00 sec
[bwa_aln_core] print alignments... 0.00 sec
[bwa_aln_core] 4 sequences have been processed.
[main] Version: 0.7.17-r1198-dirty
[main] CMD: /Library/Frameworks/R.framework/Versions/4.3-arm64/Resources/library/Rbwa/bwa samse -n 1000000000 /tmp/RtmpioJslR/chr12 /tmp/RtmpioJslR/file16f422df58923.sai /tmp/RtmpioJslR/file16f422df58923
[main] Real time: 0.030 sec; CPU: 0.016 sec
[runCrisprBwa] Using BSgenome.Hsapiens.UCSC.hg38 
[runCrisprBwa] Searching for AsCas12a protospacers 
[bwa_aln_core] calculate SA coordinate... 0.00 sec
[bwa_aln_core] write to the disk... 0.00 sec
[bwa_aln_core] 4 sequences have been processed.
[main] Version: 0.7.17-r1198-dirty
[main] CMD: /Library/Frameworks/R.framework/Versions/4.3-arm64/Resources/library/Rbwa/bwa aln -N -n 3 -l 69 -o 0 /tmp/RtmpioJslR/chr12 /tmp/RtmpioJslR/file16f4252fe7067
[main] Real time: 0.027 sec; CPU: 0.016 sec
[bwa_aln_core] convert to sequence coordinate... 0.00 sec
[bwa_aln_core] refine gapped alignments... 0.00 sec
[bwa_aln_core] print alignments... 0.00 sec
[bwa_aln_core] 4 sequences have been processed.
[main] Version: 0.7.17-r1198-dirty
[main] CMD: /Library/Frameworks/R.framework/Versions/4.3-arm64/Resources/library/Rbwa/bwa samse -n 1000000000 /tmp/RtmpioJslR/chr12 /tmp/RtmpioJslR/file16f4252fe7067.sai /tmp/RtmpioJslR/file16f4252fe7067
[main] Real time: 0.030 sec; CPU: 0.017 sec
[ FAIL 0 | WARN 0 | SKIP 0 | PASS 19 ]
> 
> proc.time()
   user  system elapsed 
 19.216   1.835  34.962