Bioconductor 3.22 Released

simPIC

This is the development version of simPIC; for the stable release version, see simPIC.

Flexible simulation of paired-insertion counts for single-cell ATAC-sequencing data


Bioconductor version: Development (3.23)

simPIC is a package for simulating single-cell ATAC-seq count data. It provides a user-friendly, well documented interface for data simulation. Functions are provided for parameter estimation, realistic scATAC-seq data simulation, and comparing real and simulated datasets.

Author: Sagrika Chugh [aut, cre] ORCID iD ORCID: 0000-0002-8050-5214 , Heejung Shim [aut], Davis McCarthy [aut]

Maintainer: Sagrika Chugh <sagrika.chugh at gmail.com>

Citation (from within R, enter citation("simPIC")):

Installation

To install this package, start R (version "4.6") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("simPIC")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

Reference Manual PDF

Details

biocViews ATACSeq, DataImport, ImmunoOncology, Sequencing, SingleCell, Software
Version 1.7.0
In Bioconductor since BioC 3.19 (R-4.4) (1.5 years)
License GPL-3
Depends R (>= 4.5.0), SingleCellExperiment
Imports BiocGenerics, checkmate (>= 2.0.0), fitdistrplus, matrixStats, actuar, Matrix, stats, SummarizedExperiment, rlang, S4Vectors, methods, scales, scuttle, edgeR, withr
System Requirements
URL https://github.com/sagrikachugh/simPIC
Bug Reports https://github.com/sagrikachugh/simPIC/issues
See More
Suggests ggplot2 (>= 3.4.0), knitr, rmarkdown, BiocStyle, testthat (>= 3.0.0), scater, scran, magick
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Follow Installation instructions to use this package in your R session.

Source Package
Windows Binary (x86_64)
macOS Binary (x86_64)
macOS Binary (arm64)
Source Repository git clone https://git.bioconductor.org/packages/simPIC
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/simPIC
Package Short Url https://bioconductor.org/packages/simPIC/
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