methyvim

This package is for version 3.6 of Bioconductor. This package has been removed from Bioconductor. For the last stable, up-to-date release version, see methyvimData.

Differential Methylation Analysis with Targeted Minimum Loss-Based Estimates of Variable Importance Measures


Bioconductor version: 3.6

This package provides facilities for differential methylation analysis based on variable importance measures (VIMs), a class of statistical target parameters that arise in causal inference. The estimation and inference procedures provided are nonparametric, relying on ensemble machine learning to flexibly assess functional relationship among covariates and the outcome of interest. These tools can be applied to differential methylation at the level of CpG sites, with valid inference after multiple hypothesis testing.

Author: Nima Hejazi [aut, cre, cph], Rachael Phillips [ctb], Alan Hubbard [ctb], Mark van der Laan [aut]

Maintainer: Nima Hejazi <nhejazi at berkeley.edu>

Citation (from within R, enter citation("methyvim")):

Installation

To install this package, start R (version "3.4") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("methyvim")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

Reference Manual PDF
NEWS Text
LICENSE Text

Details

biocViews Clustering, DNAMethylation, DifferentialMethylation, MethylSeq, MethylationArray, Software
Version 1.0.0
In Bioconductor since BioC 3.6 (R-3.4) (6.5 years)
License file LICENSE
Depends R (>= 3.4.0)
Imports stats, cluster, methods, ggplot2, gridExtra, superheat, wesanderson, magrittr, dplyr, gtools, tmle, future, doFuture, BiocParallel, BiocGenerics, SummarizedExperiment, GenomeInfoDb, bumphunter, IRanges, limma, minfi
System Requirements
URL https://github.com/nhejazi/methyvim
Bug Reports https://github.com/nhejazi/methyvim/issues
See More
Suggests testthat, knitr, rmarkdown, BiocStyle, SuperLearner, earth, nnet, gam, arm, snow, parallel, BatchJobs, minfiData, methyvimData
Linking To
Enhances
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package methyvim_1.0.0.tar.gz
Windows Binary methyvim_1.0.0.zip
Mac OS X 10.11 (El Capitan) methyvim_1.0.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/methyvim
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/methyvim
Package Short Url https://bioconductor.org/packages/methyvim/
Package Downloads Report Download Stats
Old Source Packages for BioC 3.6 Source Archive