LineagePulse
This package is for version 3.9 of Bioconductor. This package has been removed from Bioconductor. For the last stable, up-to-date release version, see LineagePulse.
Differential expression analysis and model fitting for single-cell RNA-seq data
Bioconductor version: 3.9
LineagePulse is a differential expression and expression model fitting package tailored to single-cell RNA-seq data (scRNA-seq). LineagePulse accounts for batch effects, drop-out and variable sequencing depth. One can use LineagePulse to perform longitudinal differential expression analysis across pseudotime as a continuous coordinate or between discrete groups of cells (e.g. pre-defined clusters or experimental conditions). Expression model fits can be directly extracted from LineagePulse.
Author: David S Fischer [aut, cre], Fabian Theis [ctb], Nir Yosef [ctb]
Maintainer: David S Fischer <david.fischer at helmholtz-muenchen.de>
citation("LineagePulse")
):
Installation
To install this package, start R (version "3.6") and enter:
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("LineagePulse")
For older versions of R, please refer to the appropriate Bioconductor release.
Documentation
To view documentation for the version of this package installed in your system, start R and enter:
browseVignettes("LineagePulse")
LineagePulse | HTML | R Script |
Reference Manual | ||
NEWS | Text |
Details
biocViews | CellBasedAssays, CellBiology, DifferentialExpression, GeneExpression, ImmunoOncology, Sequencing, SingleCell, Software, StatisticalMethod, TimeCourse |
Version | 1.4.0 |
In Bioconductor since | BioC 3.7 (R-3.5) (6 years) |
License | Artistic-2.0 |
Depends | |
Imports | BiocParallel, circlize, compiler, ComplexHeatmap, ggplot2, gplots, grDevices, grid, knitr, Matrix, methods, RColorBrewer, SingleCellExperiment, splines, stats, SummarizedExperiment, utils |
System Requirements | |
URL | |
Bug Reports | https://github.com/YosefLab/LineagePulse/issues |
See More
Suggests | |
Linking To | |
Enhances | |
Depends On Me | |
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Build Report | Build Report |
Package Archives
Follow Installation instructions to use this package in your R session.
Source Package | LineagePulse_1.4.0.tar.gz |
Windows Binary | LineagePulse_1.4.0.zip (32- & 64-bit) |
Mac OS X 10.11 (El Capitan) | LineagePulse_1.4.0.tgz |
Source Repository | git clone https://git.bioconductor.org/packages/LineagePulse |
Source Repository (Developer Access) | git clone git@git.bioconductor.org:packages/LineagePulse |
Bioc Package Browser | https://code.bioconductor.org/browse/LineagePulse/ |
Package Short Url | https://bioconductor.org/packages/LineagePulse/ |
Package Downloads Report | Download Stats |
Old Source Packages for BioC 3.9 | Source Archive |