2017-02-14 Updating! Adding new method: aFold to call DE via fold-change 2016-02-29 Updating! Enable the paired comparison by seting up 'paired' parameter in 'ABSDataSet' object 2015-08-24 This is the second version of ABSSeq. 1) Use NB distribution insead of GP to model the counts difference between conditions 2) Introduce an efficient outlier detection method: moderated MAD 3) Introduce penalty for dispersion estimation 4) Provide moderation of log2 fold-change at expression level and gene-specific dispersion