\name{quantileNormalization} \alias{quantileNormalization} %- Also NEED an '\alias' for EACH other topic documented here. \title{ Quantile normalization } \description{ Quantile normalization (see References) } \usage{ quantileNormalization(header, dataset, listOfArgs) } %- maybe also 'usage' for other objects documented here. \arguments{ \item{header}{ the header of a dataset file generated with \code{\link{generateDatasetFile}} } \item{dataset}{ an R data frame generated with \code{\link{generateDatasetFile}} } \item{listOfArgs}{ a list containing: - a character string specifying the column whose values will be used for normalization - 1 or 2, 1 meaning a normalization per experiment, 2 meaning a normalization per plate } } \value{ Returns a list, containing: \item{header }{the new header (with an added entry about the normalization procedure in the comments)} \item{dataset }{the new dataset with normalized values. The old values are saved in an extra column with the suffix ".old"} } \references{ B.M. Bolstad, R.A. Irizarry, M. Astrand, and T.P. Speed. A Comparison of Normalization Methods for High Density Oligonucleotide Array Data Based on Variance and Bias. Bioinformatics, 19(2): 185-193, 2003 } \examples{ data(exampleHeader, package="RNAither") data(exampleDataset, package="RNAither") normres <- quantileNormalization(header, dataset, list(2, "SigIntensity")) newheader <- normres[[1]] newdataset <- normres[[2]] } \keyword{ manip }