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### Running command:
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###   /Library/Frameworks/R.framework/Resources/bin/R CMD build --keep-empty-dirs --no-resave-data CrispRVariants
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* checking for file ‘CrispRVariants/DESCRIPTION’ ... OK
* preparing ‘CrispRVariants’:
* checking DESCRIPTION meta-information ... OK
* installing the package to build vignettes
* creating vignettes ... ERROR
--- re-building ‘user_guide.Rmd’ using rmarkdown
Loading required package: ggplot2
Loading required package: Biostrings
Loading required package: BiocGenerics

Attaching package: 'BiocGenerics'

The following objects are masked from 'package:stats':

    IQR, mad, sd, var, xtabs

The following objects are masked from 'package:base':

    Filter, Find, Map, Position, Reduce, anyDuplicated, append,
    as.data.frame, basename, cbind, colnames, dirname, do.call,
    duplicated, eval, evalq, get, grep, grepl, intersect, is.unsorted,
    lapply, mapply, match, mget, order, paste, pmax, pmax.int, pmin,
    pmin.int, rank, rbind, rownames, sapply, setdiff, sort, table,
    tapply, union, unique, unsplit, which.max, which.min

Loading required package: S4Vectors
Loading required package: stats4

Attaching package: 'S4Vectors'

The following objects are masked from 'package:base':

    I, expand.grid, unname

Loading required package: IRanges
Loading required package: XVector
Loading required package: GenomeInfoDb

Attaching package: 'Biostrings'

The following object is masked from 'package:base':

    strsplit

gdata: read.xls support for 'XLS' (Excel 97-2004) files ENABLED.

gdata: read.xls support for 'XLSX' (Excel 2007+) files ENABLED.

Attaching package: 'gdata'

The following objects are masked from 'package:IRanges':

    startsWith, trim

The following objects are masked from 'package:S4Vectors':

    first, first<-

The following object is masked from 'package:stats4':

    nobs

The following object is masked from 'package:BiocGenerics':

    combine

The following object is masked from 'package:stats':

    nobs

The following object is masked from 'package:utils':

    object.size

The following object is masked from 'package:base':

    startsWith

Quitting from lines 271-276 (user_guide.Rmd) 
Error: processing vignette 'user_guide.Rmd' failed with diagnostics:
there is no package called 'rtracklayer'
--- failed re-building ‘user_guide.Rmd’

SUMMARY: processing the following file failed:
  ‘user_guide.Rmd’

Error: Vignette re-building failed.
Execution halted