swfdr

This package is for version 3.7 of Bioconductor; for the stable, up-to-date release version, see swfdr.

Science-wise false discovery rate and proportion of true null hypotheses estimation


Bioconductor version: 3.7

This package allows users to estimate the science-wise false discovery rate from Jager and Leek, "Empirical estimates suggest most published medical research is true," 2013, Biostatistics, using an EM approach due to the presence of rounding and censoring. It also allows users to estimate the proportion of true null hypotheses in the presence of covariates, using a regression framework, as per Boca and Leek, "A regression framework for the proportion of true null hypotheses," 2015, bioRxiv preprint.

Author: Jeffrey T. Leek, Leah Jager, Simina M. Boca

Maintainer: Simina M. Boca <smb310 at georgetown.edu>, Jeffrey T. Leek <jtleek at gmail.com>

Citation (from within R, enter citation("swfdr")):

Installation

To install this package, start R (version "3.5") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("swfdr")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("swfdr")
Tutorial for swfdr package PDF R Script
Reference Manual PDF
NEWS Text

Details

biocViews MultipleComparison, Software, StatisticalMethod
Version 1.6.0
In Bioconductor since BioC 3.5 (R-3.4) (7 years)
License GPL (>= 3)
Depends R (>= 3.4)
Imports stats4, ggplot2, reshape2, stats, dplyr
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Suggests BiocStyle, knitr, rmarkdown
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package swfdr_1.6.0.tar.gz
Windows Binary swfdr_1.6.0.zip
Mac OS X 10.11 (El Capitan) swfdr_1.6.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/swfdr
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/swfdr
Package Short Url https://bioconductor.org/packages/swfdr/
Package Downloads Report Download Stats
Old Source Packages for BioC 3.7 Source Archive