podkat

This package is for version 3.7 of Bioconductor; for the stable, up-to-date release version, see podkat.

Position-Dependent Kernel Association Test


Bioconductor version: 3.7

This package provides an association test that is capable of dealing with very rare and even private variants. This is accomplished by a kernel-based approach that takes the positions of the variants into account. The test can be used for pre-processed matrix data, but also directly for variant data stored in VCF files. Association testing can be performed whole-genome, whole-exome, or restricted to pre-defined regions of interest. The test is complemented by tools for analyzing and visualizing the results.

Author: Ulrich Bodenhofer

Maintainer: Ulrich Bodenhofer <bodenhofer at bioinf.jku.at>

Citation (from within R, enter citation("podkat")):

Installation

To install this package, start R (version "3.5") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("podkat")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("podkat")
PODKAT - An R Package for Association Testing Involving Rare and Private Variants PDF R Script
Reference Manual PDF
NEWS Text

Details

biocViews Annotation, DataImport, Genetics, Sequencing, Software, VariantAnnotation, WholeGenome
Version 1.12.0
In Bioconductor since BioC 3.1 (R-3.2) (9 years)
License GPL (>= 2)
Depends R (>= 3.2.0), methods, Rsamtools, GenomicRanges
Imports Rcpp (>= 0.11.1), parallel, stats, graphics, grDevices, utils, Biobase, BiocGenerics, Matrix, GenomeInfoDb, IRanges, Biostrings, BSgenome(>= 1.32.0)
System Requirements
URL http://www.bioinf.jku.at/software/podkat/
See More
Suggests BSgenome.Hsapiens.UCSC.hg38.masked, TxDb.Hsapiens.UCSC.hg38.knownGene, BSgenome.Mmusculus.UCSC.mm10.masked, GWASTools(>= 1.13.24), VariantAnnotation, SummarizedExperiment, knitr
Linking To Rcpp, Rsamtools
Enhances
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package podkat_1.12.0.tar.gz
Windows Binary podkat_1.12.0.zip (32- & 64-bit)
Mac OS X 10.11 (El Capitan) podkat_1.12.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/podkat
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/podkat
Package Short Url https://bioconductor.org/packages/podkat/
Package Downloads Report Download Stats
Old Source Packages for BioC 3.7 Source Archive