TFHAZ

This package is for version 3.6 of Bioconductor; for the stable, up-to-date release version, see TFHAZ.

Transcription Factor High Accumulation Zones


Bioconductor version: 3.6

It finds trascription factor (TF) high accumulation DNA zones, i.e., regions along the genome where there is a high presence of different transcription factors. Starting from a dataset containing the genomic positions of TF binding regions, for each base of the selected chromosome the accumulation of TFs is computed. Three different types of accumulation (TF, region and base accumulation) are available, together with the possibility of considering, in the single base accumulation computing, the TFs present not only in that single base, but also in its neighborhood, within a window of a given width. Then, high accumulation DNA zones are defined as regions of the genome formed by contiguous bases with accumulation equal or higher than a given threshold. In addition, some functions are provided in order to analyze, visualize and compare results obtained with different input parameters.

Author: Alberto Marchesi, Marco Masseroli

Maintainer: Alberto Marchesi <alberto.march91 at gmail.com>

Citation (from within R, enter citation("TFHAZ")):

Installation

To install this package, start R (version "3.4") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("TFHAZ")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

Reference Manual PDF

Details

biocViews BiologicalQuestion, ChIPSeq, Coverage, Software, Transcription
Version 1.0.0
In Bioconductor since BioC 3.6 (R-3.4) (6.5 years)
License Artistic-2.0
Depends R (>= 3.4)
Imports GenomicRanges, S4Vectors, grDevices, graphics, stats, utils, IRanges
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package TFHAZ_1.0.0.tar.gz
Windows Binary TFHAZ_1.0.0.zip
Mac OS X 10.11 (El Capitan) TFHAZ_1.0.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/TFHAZ
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/TFHAZ
Package Short Url https://bioconductor.org/packages/TFHAZ/
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Old Source Packages for BioC 3.6 Source Archive