--- title: "Description of chromhmmData" output: rmarkdown::html_vignette vignette: > %\VignetteIndexEntry{chromhmmData} %\VignetteEngine{knitr::rmarkdown} %\VignetteEncoding{UTF-8} --- ```{r, include = FALSE} knitr::opts_chunk$set( collapse = TRUE, comment = "#>" ) ``` To install `chromhmmData` use ```{r installation,eval=FALSE} if(!requireNamespace("BiocManager", quietly = TRUE)) install.packages("BiocManager") BiocManager::install("chromhmmData") ``` ```{r setup} library(chromhmmData) ``` This package include the genomic annotations required for running `ChromHMM`. This includes: 1. `CHROMSIZES`: text files with the chromosomes' sizes 2. `COORDS`: bed files with the coordinates of different genomic features 3. `ANCHORFILES`: text files with transcription start and end sites of known genes The annotations for four different genomes are included in the package. Those are the human `hg18` and `hg19` and the mouse `mm10` and `mm9`. Use `system.file` to access the files and directorys. For example ```{r example} # access a directory chromsizes <- system.file('extdata/CHROMSIZES', package = 'chromhmmData') dir(chromsizes) # access a file system.file('extdata/CHROMSIZES', 'hg19.txt', package = 'chromhmmData') ``` These annotation files are obtained from [`ChromHMM`](https://github.com/jernst98/ChromHMM) source code repository. ```{r sessioninfo} sessionInfo() ```