VariantAnnotation

This package is for version 3.13 of Bioconductor; for the stable, up-to-date release version, see VariantAnnotation.

Annotation of Genetic Variants


Bioconductor version: 3.13

Annotate variants, compute amino acid coding changes, predict coding outcomes.

Author: Bioconductor Package Maintainer [aut, cre], Valerie Oberchain [aut], Martin Morgan [aut], Michael Lawrence [aut], Stephanie Gogarten [ctb]

Maintainer: Bioconductor Package Maintainer <maintainer at bioconductor.org>

Citation (from within R, enter citation("VariantAnnotation")):

Installation

To install this package, start R (version "4.1") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("VariantAnnotation")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("VariantAnnotation")
1. Introduction to VariantAnnotation PDF R Script
2. Using filterVcf to Select Variants from VCF Files PDF R Script
Reference Manual PDF
NEWS Text
Reading VCF data Video

Details

biocViews Annotation, DataImport, Genetics, SNP, Sequencing, Software, VariantAnnotation
Version 1.38.0
In Bioconductor since BioC 2.9 (R-2.14) (12.5 years)
License Artistic-2.0
Depends R (>= 4.0.0), methods, BiocGenerics(>= 0.37.0), MatrixGenerics, GenomeInfoDb(>= 1.15.2), GenomicRanges(>= 1.41.5), SummarizedExperiment(>= 1.19.5), Rsamtools(>= 1.99.0)
Imports utils, DBI, zlibbioc, Biobase, S4Vectors(>= 0.27.12), IRanges(>= 2.23.9), XVector(>= 0.29.2), Biostrings(>= 2.57.2), AnnotationDbi(>= 1.27.9), rtracklayer(>= 1.39.7), BSgenome(>= 1.47.3), GenomicFeatures(>= 1.31.3)
System Requirements GNU make
URL
See More
Suggests RUnit, AnnotationHub, BSgenome.Hsapiens.UCSC.hg19, TxDb.Hsapiens.UCSC.hg19.knownGene, SNPlocs.Hsapiens.dbSNP.20101109, SIFT.Hsapiens.dbSNP132, SIFT.Hsapiens.dbSNP137, PolyPhen.Hsapiens.dbSNP131, snpStats, ggplot2, BiocStyle
Linking To S4Vectors, IRanges, XVector, Biostrings, Rhtslib
Enhances
Depends On Me annotation, cgdv17, CNVrd2, deepSNV, ensemblVEP, genotypeeval, HelloRanges, HTSeqGenie, myvariant, PolyPhen.Hsapiens.dbSNP131, PureCN, R453Plus1Toolbox, RareVariantVis, seqCAT, sequencing, SIFT.Hsapiens.dbSNP132, SIFT.Hsapiens.dbSNP137, signeR, SomaticSignatures, StructuralVariantAnnotation, VariantFiltering, variants, VariantTools, VariantToolsData
Imports Me AllelicImbalance, APAlyzer, appreci8R, BadRegionFinder, BBCAnalyzer, biovizBase, biscuiteer, CNVfilteR, CopyNumberPlots, COSMIC.67, customProDB, DAMEfinder, decompTumor2Sig, DominoEffect, epialleleR, fcScan, GA4GHclient, genbankr, GenomicFiles, GenVisR, ggbio, gmapR, gwascat, gwasurvivr, icetea, igvR, karyoploteR, ldblock, MADSEQ, methyAnalysis, MMAPPR2, motifbreakR, musicatk, MutationalPatterns, scoreInvHap, SigsPack, SNPhood, systemPipeR, TitanCNA, tLOH, TVTB, Uniquorn, VCFArray, XCIR, YAPSA
Suggests Me AnnotationHub, AshkenazimSonChr21, BiocParallel, cellbaseR, CNVgears, CrispRVariants, GenomicRanges, GenomicScores, GeuvadisTranscriptExpr, GWASTools, omicsPrint, podkat, RVS, SeqArray, splatter, supersigs, trackViewer, trio, vtpnet
Links To Me
Build Report Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package VariantAnnotation_1.38.0.tar.gz
Windows Binary VariantAnnotation_1.38.0.zip
macOS 10.13 (High Sierra) VariantAnnotation_1.38.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/VariantAnnotation
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/VariantAnnotation
Bioc Package Browser https://code.bioconductor.org/browse/VariantAnnotation/
Package Short Url https://bioconductor.org/packages/VariantAnnotation/
Package Downloads Report Download Stats
Old Source Packages for BioC 3.13 Source Archive